View source for Auer rod

[[Image:Auer_Rods_in_Leukemic_Blast_(2434847298).jpg | thumb | Micrograph showing an Auer rod in a blast. [[Wright stain]]. (WC)]]
'''Auer rod''' a microscopic finding typical of some types of [[acute myeloid leukemia]] and seen in [[myelodysplastic syndromes]].

It may be referred to as an '''Auer body'''.

==General==
*Consider to be an indicator of dysplasia or malignancy.<ref name=pmid18947869>{{Cite journal  | last1 = Yoshida | first1 = Y. | last2 = Oguma | first2 = S. | last3 = Ohno | first3 = H. | last4 = Auer | first4 = J. | title = John Auer and Auer rods; controversies revisited. | journal = Leuk Res | volume = 33 | issue = 5 | pages = 614-6 | month = May | year = 2009 | doi = 10.1016/j.leukres.2008.09.014 | PMID = 18947869 }}</ref>
*Derived from lysosomes.<ref name=pmid1712539/>

==Microscopic==
Features:
*Needle-like cytoplasmic bodies - classic appearance.<ref name=pmid15434012>{{Cite journal  | last1 = ACKERMAN | first1 = GA. | title = Microscopic and histochemical studies on the Auer bodies in leukemic cells. | journal = Blood | volume = 5 | issue = 9 | pages = 847-63 | month = Sep | year = 1950 | doi =  | PMID = 15434012 }}</ref>
**Other shapes: comma-like, diamond-like, rectangular, rarely glandular or corkscrew-like.

DDx:
*Auer-rod like inclusions - may be seen in [[multiple myeloma]]<ref name=pmid24338920>{{Cite journal  | last1 = Abdulsalam | first1 = AH. | last2 = Bain | first2 = BJ. | title = Auer-rod like inclusions in multiple myeloma. | journal = Am J Hematol | volume = 89 | issue = 3 | pages = 338 | month = Mar | year = 2014 | doi = 10.1002/ajh.23648 | PMID = 24338920 }}</ref> or lymphoma cells.<ref name=pmid1712539>{{Cite journal  | last1 = Groom | first1 = DA. | last2 = Wong | first2 = D. | last3 = Brynes | first3 = RK. | last4 = Macaulay | first4 = LK. | title = Auer rod-like inclusions in circulating lymphoma cells. | journal = Am J Clin Pathol | volume = 96 | issue = 1 | pages = 111-5 | month = Jul | year = 1991 | doi =  | PMID = 1712539 }}</ref>

===Images===
<gallery>
Image:Auer_rods.PNG | Auer rods. (WC)
Image:Faggot cell in AML-M3.jpg | Abundant Auer rods in a Faggot cell. (WC)
</gallery>

==See als==
*[[Acute myeloid leukemia]].
*[[Russell bodies]].

==References==
{{Reflist|2}}

[[Category:Basics]]