Difference between revisions of "Haematopoiesis"

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===Microscopic===
===Microscopic===
One should see three cell lines:<ref>URL: [http://emedicine.medscape.com/article/199003-overview http://emedicine.medscape.com/article/199003-overview]. Accessed on: 22 November 2010.</ref>
One should see three cell lines:<ref>URL: [http://emedicine.medscape.com/article/199003-overview http://emedicine.medscape.com/article/199003-overview]. Accessed on: 22 November 2010.</ref>
*Erythroid (red blood cells).  
*Erythroid cells.  
*Myeloid (white blood cells).  
*Myeloid cells.  
*Megakaryocytic (platelets).
*Megakaryocytes.


Images:
Images:
*[http://commons.wikimedia.org/wiki/File:Extramedullary_haematopoiesis_-_endometrial_polyp_-_high_mag.jpg Extramedullary haematopoiesis - sort-of - high mag. (WC)] - shows nucleated [[RBC]]s.
*[http://commons.wikimedia.org/wiki/File:Extramedullary_haematopoiesis_-_endometrial_polyp_-_high_mag.jpg Nucleated RBCs - high mag. (WC)].
*[http://www.ouhsc.edu/histology/Glass%20slides/75_16.jpg Megakaryocyte (ouhsc.edu)].<ref>URL: [http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html]. Accessed on: 22 November 2010.</ref>
*[http://www.ouhsc.edu/histology/Glass%20slides/75_16.jpg Megakaryocyte (ouhsc.edu)].<ref>URL: [http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html]. Accessed on: 22 November 2010.</ref>



Revision as of 18:50, 14 January 2012

Haematopoiesis is the making of blood. Problems in haematopoiesis are numberous and the domain of hematology and hematopathology.

Normal haematopoiesis

Microscopic

One should see three cell lines:[1]

  • Erythroid cells.
  • Myeloid cells.
  • Megakaryocytes.

Images:

Extramedullary haematopoiesis

  • Abbreviated EMH.

General

  • In adults it is a compensatory mechanism for bone marrow dysfunction.

Locations:[3]

Microscopic

Features:

  • Erythroid cells - esp. nucleated red blood cells.
  • Myeloid - granulocytes and granulocyte precursors.
  • Megakaryocytes - Large cells (50-100 μm) with abundant cytoplasm.
    • Make platelets.

Images:

See also

References

  1. URL: http://emedicine.medscape.com/article/199003-overview. Accessed on: 22 November 2010.
  2. URL: http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html. Accessed on: 22 November 2010.
  3. URL: http://path.upmc.edu/cases/case283/dx.html. Accessed on: 14 January 2012.

External links