Difference between revisions of "Hemophagocytic syndrome"
Jump to navigation
Jump to search
m (+cat) |
(more) |
||
| Line 7: | Line 7: | ||
*Jaundice. | *Jaundice. | ||
==Classification== | |||
*HIV | Classified by etiology:<ref name=pmid20383897>{{cite journal |author=Gupta S, Weitzman S |title=Primary and secondary hemophagocytic lymphohistiocytosis: clinical features, pathogenesis and therapy |journal=Expert Rev Clin Immunol |volume=6 |issue=1 |pages=137–54 |year=2010 |month=January |pmid=20383897 |doi= |url=}}</ref> | ||
* | #Primary, i.e. inherited. | ||
#Secondary: | |||
#*Infection, e.g. EBV, HIV. | |||
#*Malignancy. | |||
#*Rheumatologic condition. | |||
==Microscopic== | ==Microscopic== | ||
| Line 17: | Line 21: | ||
**Leukocytes. | **Leukocytes. | ||
**Platelets. | **Platelets. | ||
Images: [http://en.wikipedia.org/wiki/File:Haemophagocytic_lymphohistiocytosis_Bone_marrow.JPG HLH (WC)]. | |||
==See also== | ==See also== | ||
Revision as of 21:21, 13 August 2010
Hemophagocytic syndrome, also known as hemophagocytic lymphohistiocytosis, is a rare condition often associated with viral infections.
Clinical
Features:[1]
- Fever.
- Splenomegaly.
- Jaundice.
Classification
Classified by etiology:[2]
- Primary, i.e. inherited.
- Secondary:
- Infection, e.g. EBV, HIV.
- Malignancy.
- Rheumatologic condition.
Microscopic
Features:[1]
- Macrophages with phagocytosed:
- Erythrocytes.
- Leukocytes.
- Platelets.
Images: HLH (WC).
See also
References
- ↑ 1.0 1.1 Fisman DN (2000). "Hemophagocytic syndromes and infection". Emerging Infect. Dis. 6 (6): 601–8. PMC 2640913. PMID 11076718. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640913/?tool=pubmed.
- ↑ Gupta S, Weitzman S (January 2010). "Primary and secondary hemophagocytic lymphohistiocytosis: clinical features, pathogenesis and therapy". Expert Rev Clin Immunol 6 (1): 137–54. PMID 20383897.