Difference between revisions of "Scleroderma"
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Revision as of 04:30, 24 March 2012
Scleroderma is a disease that keeps rheumatologists busy.
General
Clinical:
- Anti-centromere antibody (ACA) +ve.
- Common in limited systemic scleroderma, AKA CREST syndrome.
- Scl-70 (topoisomerase I) +ve.
- Common in diffuse scleroderma.
CREST syndrome:
- Calcinosis.
- Raynaud's phenomenon.
- Esophageal dysmotility.
- Sclerodactyly.
- Telangiectasia.