Difference between revisions of "Behçet's syndrome"
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==General== | ==General== | ||
Etiology: | Etiology: | ||
*Unknown - hypothesized to be infectious due to the epidemiology.<ref name= | *Unknown - hypothesized to be infectious due to the epidemiology,<ref name=pmid22100288/> | ||
on a background of genetic susceptibility.<ref name=pmid17207160/> | |||
===Clinical=== | ===Clinical=== |
Revision as of 23:10, 1 June 2012
Behçet's syndrome, also Behçet's disease, is a rare disorder classically described as the triad of:[1]
- Oral aphthous ulcers.
- Genital ulcers.
- Uveitis
General
Etiology:
- Unknown - hypothesized to be infectious due to the epidemiology,[2]
on a background of genetic susceptibility.[3]
Clinical
Microscopic
Features - small vessel vasculitis:[2][3]
- Fibrinoid necrosis of the vessel walls.
- Inflammatory cells in the blood vessel walls.
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 109650
- ↑ 2.0 2.1 2.2 Hatemi, G.; Yazici, H. (Jun 2011). "Behçet's syndrome and micro-organisms.". Best Pract Res Clin Rheumatol 25 (3): 389-406. doi:10.1016/j.berh.2011.05.002. PMID 22100288.
- ↑ 3.0 3.1 Kalayciyan, A.; Zouboulis, C. (Jan 2007). "An update on Behçet's disease.". J Eur Acad Dermatol Venereol 21 (1): 1-10. doi:10.1111/j.1468-3083.2006.01863.x. PMID 17207160.