Difference between revisions of "Behçet's syndrome"
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#Uveitis | #Uveitis | ||
== | ==General== | ||
* | Etiology: | ||
*Unknown - hypothesized to be infectious (due to the epidemiology<ref name=pmid22100288/>) on a background of genetic susceptibility.<ref name=pmid17207160/> | |||
===Clinical=== | |||
*''Pathergy'' also | *''[[Pathergy]]''<ref name=pmid22100288>{{Cite journal | last1 = Hatemi | first1 = G. | last2 = Yazici | first2 = H. | title = Behçet's syndrome and micro-organisms. | journal = Best Pract Res Clin Rheumatol | volume = 25 | issue = 3 | pages = 389-406 | month = Jun | year = 2011 | doi = 10.1016/j.berh.2011.05.002 | PMID = 22100288 }} | ||
</ref> = minor trauma (to the skin) results in a non-healing lesion. | |||
==Microscopic== | |||
Features - small vessel [[vasculitis]]:<ref name=pmid22100288/><ref name=pmid17207160>{{Cite journal | last1 = Kalayciyan | first1 = A. | last2 = Zouboulis | first2 = C. | title = An update on Behçet's disease. | journal = J Eur Acad Dermatol Venereol | volume = 21 | issue = 1 | pages = 1-10 | month = Jan | year = 2007 | doi = 10.1111/j.1468-3083.2006.01863.x | PMID = 17207160 }}</ref> | |||
*[[Fibrinoid necrosis]] of the vessel walls. | |||
*Inflammatory cells in the blood vessel walls. | |||
==See also== | |||
*[[Vasculitides]]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
Latest revision as of 23:12, 1 June 2012
Behçet's syndrome, also Behçet's disease, is a rare disorder classically described as the triad of:[1]
- Oral aphthous ulcers.
- Genital ulcers.
- Uveitis
General
Etiology:
- Unknown - hypothesized to be infectious (due to the epidemiology[2]) on a background of genetic susceptibility.[3]
Clinical
Microscopic
Features - small vessel vasculitis:[2][3]
- Fibrinoid necrosis of the vessel walls.
- Inflammatory cells in the blood vessel walls.
See also
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 109650
- ↑ 2.0 2.1 2.2 Hatemi, G.; Yazici, H. (Jun 2011). "Behçet's syndrome and micro-organisms.". Best Pract Res Clin Rheumatol 25 (3): 389-406. doi:10.1016/j.berh.2011.05.002. PMID 22100288.
- ↑ 3.0 3.1 Kalayciyan, A.; Zouboulis, C. (Jan 2007). "An update on Behçet's disease.". J Eur Acad Dermatol Venereol 21 (1): 1-10. doi:10.1111/j.1468-3083.2006.01863.x. PMID 17207160.