Difference between revisions of "Adamantinoma"
Jump to navigation
Jump to search
(+cat.) |
(split out) |
||
| Line 1: | Line 1: | ||
# | '''Adamantinoma''' is an uncommon benign [[bone tumour]]. It should '''not''' be confused with ''[[adenomatoid tumour]]''. | ||
==General== | |||
Features:<ref name=Ref_WMSP650>{{Ref WMSP|650}}</ref> | |||
*Rare: < 1% of bone tumours. | |||
*25-35 years old. | |||
*Benign, may be locally aggressive. | |||
*Cousin of [[ameloblastoma]]. (???) | |||
==Gross== | |||
*Tibia or fibula. | |||
===Radiology=== | |||
*Intracortical, radiolucent. | |||
==Microscopic== | |||
Features: | |||
*Biphasic tumour: | |||
*#Fibrous/spindle cell component. | |||
*#Epithelial component. | |||
DDx:<ref name=pathcon_adam>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2]. Accessed on: 28 April 2011.</ref> | |||
*Vascular tumours ([[Epithelioid hemangioendothelioma]]). | |||
*[[Metastatic carcinoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Adamantinoma_-_intermed_mag.jpg | Adamantinoma - intermed. mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://southbaypath.org/CaseImages/sb5260/AdamantinomaBiopsy3.jpg Adamantinoma (southbaypath.org)].<ref>URL: [http://southbaypath.org/CaseImages/sb5260/sb5260.htm http://southbaypath.org/CaseImages/sb5260/sb5260.htm]. Accessed on: 7 December 2010.</ref> | |||
==IHC== | |||
Features:<ref name=pathcon_adam/> | |||
*CK14 +ve (HMWK).<ref>URL: [http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm]. Accessed on: 28 April 2011.</ref> | |||
*CK19 +ve (LMWK). | |||
*CK8/18 -ve (LMWK). | |||
==See also== | |||
*[[Chondro-osseous tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Chondro-osseous tumours]] | |||
Revision as of 22:01, 29 August 2013
Adamantinoma is an uncommon benign bone tumour. It should not be confused with adenomatoid tumour.
General
Features:[1]
- Rare: < 1% of bone tumours.
- 25-35 years old.
- Benign, may be locally aggressive.
- Cousin of ameloblastoma. (???)
Gross
- Tibia or fibula.
Radiology
- Intracortical, radiolucent.
Microscopic
Features:
- Biphasic tumour:
- Fibrous/spindle cell component.
- Epithelial component.
DDx:[2]
- Vascular tumours (Epithelioid hemangioendothelioma).
- Metastatic carcinoma.
Images
Adamantinoma - intermed. mag. (WC)
www:
IHC
Features:[2]
- CK14 +ve (HMWK).[4]
- CK19 +ve (LMWK).
- CK8/18 -ve (LMWK).
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 650. ISBN 978-0781765275.
- ↑ 2.0 2.1 URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970057-2. Accessed on: 28 April 2011.
- ↑ URL: http://southbaypath.org/CaseImages/sb5260/sb5260.htm. Accessed on: 7 December 2010.
- ↑ URL: http://www.nordiqc.org/Epitopes/Cytokeratins/cytokeratins.htm. Accessed on: 28 April 2011.