Difference between revisions of "Fetal autopsy"

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===Gross===
===Gross===
*Autoamputation of appendages and body wall defects +/- anomalies of internal organs.  
*Autoamputation of appendages and body wall defects +/- anomalies of internal organs.
 
==Developmental stuff==
*Chiari malformations (from least severe to most severe):
**Chiari type I.
**Chiari type II.
**Chiari type III.
*Dandy-Walker syndrome.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q12-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q12-Ans.htm]. Accessed on: 26 October 2010.</ref>
**Complete or partial agenesis of the vermis.
**Cystic dilatation of the fourth ventricle.
**Large posterior fossa.


==See also==
==See also==

Revision as of 20:43, 26 October 2010

The fetal autopsy is done to determine the cause of death in a fetus. An introduction to the autopsy is in the autopsy article.

External exam

Post-mortem changes

Sequences of changes with intrauterine death:[1]

  • Normal ~0-12 hours.
  • Skin blistering - usu. prominent on head ~12-48 hours.
  • Moderate skin separation (sloughing) - usu. hands & feet ~48-72 hours
  • Massive skin separation and loosing of symphysis menti (midline mandible), symphysis pubis ~72+ hours.

Common measures[2]

  • Body mass (weight).
  • Crown-to-heel length.
  • Crown-to-rump length.
  • Occipito-frontal circumference.
  • Chest circumference - at nipples.
  • Abdominal circumference - at umbilicus.

Routinue sections

  1. Rib.
  2. Thymus, skin, diaphragm, psoas muscle.
  3. Rectum, duodenum, ileocecal region, mesentery.
  4. Adrenal gland.
  5. Kidney.
  6. Bladder.
  7. Internal genitalia.
  8. Spleen.
  9. Stomach, GE junction, GD junction, pancreas.
  10. Liver.
  11. Right lung.
  12. Left lung.
  13. Heart.
  14. Upper airway with thyroid.
  15. Pituitary.

Histology

Adrenal gland

  • Centre regresses.

Kidney

  • Cortex regresses.

Lung

Thymus

  • Hassall's corpuscles (thymic corpuscle).

Image: Thymic corpuscle (WC).

Amnion rupture sequence

A term that encompasses:[3]

  • Amniotic band syndrome.
  • Amniotic adhesion sequence.
  • Limb-body wall complex

Etiology

  • Congenital.
    • Karyotypes is normal.

Gross

  • Autoamputation of appendages and body wall defects +/- anomalies of internal organs.

Developmental stuff

  • Chiari malformations (from least severe to most severe):
    • Chiari type I.
    • Chiari type II.
    • Chiari type III.
  • Dandy-Walker syndrome.[4]
    • Complete or partial agenesis of the vermis.
    • Cystic dilatation of the fourth ventricle.
    • Large posterior fossa.

See also

References

  1. ↑ Burton, Julian L.; Rutty, Guy N. (2010). The Hospital Autopsy A Manual of Fundamental Autopsy Practice (3rd ed.). Oxford University Press. pp. 191. ISBN 978-0340965146.
  2. ↑ Burton, Julian L.; Rutty, Guy N. (2010). The Hospital Autopsy A Manual of Fundamental Autopsy Practice (3rd ed.). Oxford University Press. pp. 196, 198. ISBN 978-0340965146.
  3. ↑ URL: http://moon.ouhsc.edu/kfung/jty1/neurotest/Q11-Ans.htm. Accessed on: 26 October 2010.
  4. ↑ URL: http://moon.ouhsc.edu/kfung/jty1/neurotest/Q12-Ans.htm. Accessed on: 26 October 2010.
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