Difference between revisions of "Adenocarcinoma of the urinary bladder"

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*Nuclear pleomorphism.
*Nuclear pleomorphism.
*Glandular differentiation.
*Glandular differentiation.
*No urothelial differentiation '''important'''.<ref name=pmid23451748>{{Cite journal  | last1 = Zhong | first1 = M. | last2 = Gersbach | first2 = E. | last3 = Rohan | first3 = SM. | last4 = Yang | first4 = XJ. | title = Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance. | journal = Arch Pathol Lab Med | volume = 137 | issue = 3 | pages = 371-81 | month = Mar | year = 2013 | doi = 10.5858/arpa.2012-0076-RA | PMID = 23451748 }}</ref>
*No urothelial differentiation - '''important'''.<ref name=pmid23451748>{{Cite journal  | last1 = Zhong | first1 = M. | last2 = Gersbach | first2 = E. | last3 = Rohan | first3 = SM. | last4 = Yang | first4 = XJ. | title = Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance. | journal = Arch Pathol Lab Med | volume = 137 | issue = 3 | pages = 371-81 | month = Mar | year = 2013 | doi = 10.5858/arpa.2012-0076-RA | PMID = 23451748 }}</ref>


DDx:
DDx:

Revision as of 01:10, 6 December 2013

Adenocarcinoma of the urinary bladder, also primary adenocarcinoma of the urinary bladder, is a very uncommon malignant bladder tumour.

General

Clinical:

Microscopic

Features:

  • Nuclear pleomorphism.
  • Glandular differentiation.
  • No urothelial differentiation - important.[2]

DDx:

IHC

Features - variable:[3]

  • CK7 +ve.
  • CK20 +ve.

See also

References

  1. 1.0 1.1 Ranadive, NU.; Trivedi, VD.; Gadgil, NM. (Oct 1999). "Primary adenocarcinoma of the urinary bladder: a study of 6 cases from the pathologist's point of view.". Arch Esp Urol 52 (8): 906-11. PMID 11762445.
  2. Zhong, M.; Gersbach, E.; Rohan, SM.; Yang, XJ. (Mar 2013). "Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance.". Arch Pathol Lab Med 137 (3): 371-81. doi:10.5858/arpa.2012-0076-RA. PMID 23451748.
  3. Roy, S.; Parwani, AV. (Dec 2011). "Adenocarcinoma of the urinary bladder.". Arch Pathol Lab Med 135 (12): 1601-5. doi:10.5858/arpa.2009-0713-RS. PMID 22129192.