Difference between revisions of "Penis"

From Libre Pathology
Jump to navigation Jump to search
Line 141: Line 141:


==Squamous cell carcinoma of the penis==
==Squamous cell carcinoma of the penis==
===General===
{{Main|Squamous cell carcinoma of the penis}}
*Not very common overall.<ref name=pmid24119832>{{Cite journal  | last1 = Burt | first1 = LM. | last2 = Shrieve | first2 = DC. | last3 = Tward | first3 = JD. | title = Stage presentation, care patterns, and treatment outcomes for squamous cell carcinoma of the penis. | journal = Int J Radiat Oncol Biol Phys | volume = 88 | issue = 1 | pages = 94-100 | month = Jan | year = 2014 | doi = 10.1016/j.ijrobp.2013.08.013 | PMID = 24119832 }}</ref>
*Most common form of penis cancer.
**Non-squamous penis cancer only ~5% of cases.<ref name=pmid24292119>{{Cite journal  | last1 = Moses | first1 = KA. | last2 = Sfakianos | first2 = JP. | last3 = Winer | first3 = A. | last4 = Bernstein | first4 = M. | last5 = Russo | first5 = P. | last6 = Dalbagni | first6 = G. | title = Non-squamous cell carcinoma of the penis: single-center, 15-year experience. | journal = World J Urol | volume =  | issue =  | pages =  | month = Dec | year = 2013 | doi = 10.1007/s00345-013-1216-y | PMID = 24292119 }}</ref>
 
Epidemiology:<ref name=pmid24119832/>
*Median age ~ 67 years old.
*Usually a good outcome - 5 year cause specific survival ~ 81%.<ref name=pmid24119832/>
 
===Microscopic===
Features:
*See ''[[squamous cell carcinoma]]''.
 
Notes:
*Usually grade 2.<ref name=pmid24119832/>
 
===Sign out===
<pre>
TIP OF PENIS, PARTIAL PENECTOMY:
- INVASIVE SQUAMOUS CELL CARCINOMA, MODERATELY DIFFERENTIATED.
-- SURGICAL MARGINS NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.
-- PLEASE SEE TUMOUR SUMMARY.
</pre>


=See also=
=See also=

Revision as of 18:21, 31 December 2013

The penis is occasionally afflicted by disease that the pathologist see.

It is afflicted by common skin pathologies.

Diseases

Inflammatory

Infectious

Other non-tumour

Pre-cancerous

Neoplastic

Others:

Specific conditions

Phimosis

General

  • Cannot retract foreskin.
  • This is a clinical diagnosis.

Microscopic

Features:[1]

  • +/-Inflammation.
  • Fibrosis.

Notes: Findings non-specific.

DDx - general:

Sign out

FORESKIN, CIRCUMCISION:
- SKIN WITH PATCHY MILD NONSPECIFIC INFLAMMATION.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.

FORESKIN, EXCISION:
- KERATINIZED SQUAMOUS EPITHELIUM WITH PATCHY MILD NON-SPECIFIC
  SUBEPITHELIAL INFLAMMATION.
- NEGATIVE FOR MALIGNANCY.

FORESKIN, CIRCUMCISION:
- BENIGN KERATINIZED SQUAMOUS EPITHELIUM.
- FIBROUS SUBEPITHELIAL TISSUE WITH MINIMAL PATCHY NONSPECIFIC INFLAMMATION.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.

Micro

The sections show skin with mild patchy chronic inflammation, consisting predominantly of lymphocytes, at the dermal-epidermal junction. The epidermis matures to the surface, has rete ridges and is of a normal thickness. Focally, parakeratosis is present. No significant nuclear atypia is identified.

Penile fibromatosis

Main article: Fibromatosis
  • AKA Peyronie's disease.

General

  • Prevalence ~5%.[2]

Treatment:

  • Conservative versus surgery.

Gross

  • Abnormal curvature of the penis, esp. in the erect state.

Microscopic

Features:[2]

  • Tunica albuginea fibrosis.

Zoon balanitis

  • AKA balanitis circumscripta plasmacellularis.[3]
  • AKA plasma cell balanitis.[4]

General

  • Balanitis = inflammation of glands penis.
  • Rare.
  • Uncircumsized men.

Microscopic

Features:[3]

DDx:

Sign out

PENILE FORESKIN, CIRCUMCISION:
- COMPATIBLE WITH PLASMA CELL BALANITIS (ZOON BALANITIS), SEE COMMENT.

COMMENT:
A treponemal infection should be considered clinically.

Squamous cell carcinoma of the penis

Main article: Squamous cell carcinoma of the penis

See also

References

  1. ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 391. ISBN 978-0781765275.
  2. ↑ 2.0 2.1 Serefoglu, EC.; Hellstrom, WJ. (Dec 2011). "Treatment of Peyronie's disease: 2012 update.". Curr Urol Rep 12 (6): 444-52. doi:10.1007/s11934-011-0212-2. PMID 21818660.
  3. ↑ 3.0 3.1 Balato, N.; Scalvenzi, M.; La Bella, S.; Di Costanzo, L. (2009). "Zoon's Balanitis: Benign or Premalignant Lesion?". Case Rep Dermatol 1 (1): 7-10. doi:10.1159/000210440. PMID 20652106.
  4. ↑ Korenaga, D.; Kanematsu, T.; Watanabe, A.; Maehara, Y.; Kitano, S.; Sugimachi, K. (Feb 1991). "Clinical management of gastric cancer and concomitant esophagogastric varices.". J Surg Oncol 46 (2): 91-6. PMID 1992223.

External links

Retrieved from "https://librepathology.org/w/index.php?title=Penis&oldid=27345"