Difference between revisions of "Mammary hamartoma"
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# | '''Mammary hamartoma''', also '''breast hamartoma''', is an uncommon benign pathology of the [[breast]]. | ||
==General== | |||
*Benign. | |||
*Disordered growth - see ''[[hamartoma]]''. | |||
==Gross== | |||
*Well-circumscribed - '''key feature'''. | |||
==Microscopic== | |||
Features:<ref name=Ref_BP117>{{Ref BP|117}}</ref> | |||
*Disordered arrangement of ductal and lobular structures. | |||
*Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present. | |||
*Variable features:<ref name=surgpath_stan>URL: [http://surgpathcriteria.stanford.edu/breast/mammhamart/ http://surgpathcriteria.stanford.edu/breast/mammhamart/]. Accessed on: 4 October 2011.</ref> | |||
*#Adipose tissue - predominant. | |||
*#Dense fibrosis tissue - predominant. | |||
*#Cystic glandular dilation. | |||
Notes: | |||
*If adipose tissue predominates; it may be labeled ''adenolipoma''.<ref name=surgpath_stan>URL: [http://surgpathcriteria.stanford.edu/breast/mammhamart/ http://surgpathcriteria.stanford.edu/breast/mammhamart/]. Accessed on: 4 October 2011.</ref> | |||
DDx: | |||
*[[Fibroadenoma]] - may have adipose tissue. | |||
*[[Phyllodes tumour]] - may have adipose tissue. | |||
*[[Pseudoangiomatous stromal hyperplasia]]. | |||
*[[Fibrocystic changes]]. | |||
===Images=== | |||
*[http://www.breastpathology.info/sub-pages-iotw/2008/18.html Mammary hamartoma (breastpathology.info)]. | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/figure/f2/ Mammary hamartoma (nih.gov)].<ref name=pmid12461066>{{Cite journal | last1 = Tse | first1 = GM. | last2 = Law | first2 = BK. | last3 = Ma | first3 = TK. | last4 = Chan | first4 = AB. | last5 = Pang | first5 = LM. | last6 = Chu | first6 = WC. | last7 = Cheung | first7 = HS. | title = Hamartoma of the breast: a clinicopathological review. | journal = J Clin Pathol | volume = 55 | issue = 12 | pages = 951-4 | month = Dec | year = 2002 | doi = | PMID = 12461066 | PMC = 1769817 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/}}</ref> | |||
==IHC== | |||
*None - it's a [[H&E]] diagnosis. | |||
==See also== | |||
*[[Breast pathology]]. | |||
*[[Hamartoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Breast pathology]] | |||
Latest revision as of 04:32, 16 February 2014
Mammary hamartoma, also breast hamartoma, is an uncommon benign pathology of the breast.
General
- Benign.
- Disordered growth - see hamartoma.
Gross
- Well-circumscribed - key feature.
Microscopic
Features:[1]
- Disordered arrangement of ductal and lobular structures.
- Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present.
- Variable features:[2]
- Adipose tissue - predominant.
- Dense fibrosis tissue - predominant.
- Cystic glandular dilation.
Notes:
- If adipose tissue predominates; it may be labeled adenolipoma.[2]
DDx:
- Fibroadenoma - may have adipose tissue.
- Phyllodes tumour - may have adipose tissue.
- Pseudoangiomatous stromal hyperplasia.
- Fibrocystic changes.
Images
IHC
- None - it's a H&E diagnosis.
See also
References
- ↑ O'Malley, Frances P.; Pinder, Sarah E. (2006). Breast Pathology: A Volume in Foundations in Diagnostic Pathology series (1st ed.). Churchill Livingstone. pp. 117. ISBN 978-0443066801.
- ↑ 2.0 2.1 URL: http://surgpathcriteria.stanford.edu/breast/mammhamart/. Accessed on: 4 October 2011.
- ↑ Tse, GM.; Law, BK.; Ma, TK.; Chan, AB.; Pang, LM.; Chu, WC.; Cheung, HS. (Dec 2002). "Hamartoma of the breast: a clinicopathological review.". J Clin Pathol 55 (12): 951-4. PMC 1769817. PMID 12461066. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/.