Difference between revisions of "Solitary fibrous tumour of the pleura"

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*Uncommon overall.<ref name=pmid24326857/>
*Uncommon overall.<ref name=pmid24326857/>
**Common for the anatomical site.
**Common for the anatomical site.
*Benign.
*Usually benign.
*Slow growing.<ref name=pmid24326857>{{Cite journal  | last1 = Mordenti | first1 = P. | last2 = Di Cicilia | first2 = R. | last3 = Delfanti | first3 = R. | last4 = Capelli | first4 = P. | last5 = Paties | first5 = C. | last6 = Cavanna | first6 = L. | title = Solitary fibrous tumors of the pleura: a case report and review of the literature. | journal = Tumori | volume = 99 | issue = 4 | pages = e177-83 | month =  | year =  | doi = 10.1700/1361.15120 | PMID = 24326857 }}</ref>
*Slow growing.<ref name=pmid24326857>{{Cite journal  | last1 = Mordenti | first1 = P. | last2 = Di Cicilia | first2 = R. | last3 = Delfanti | first3 = R. | last4 = Capelli | first4 = P. | last5 = Paties | first5 = C. | last6 = Cavanna | first6 = L. | title = Solitary fibrous tumors of the pleura: a case report and review of the literature. | journal = Tumori | volume = 99 | issue = 4 | pages = e177-83 | month =  | year =  | doi = 10.1700/1361.15120 | PMID = 24326857 }}</ref>
*Elderly.
*Elderly.

Revision as of 03:34, 18 February 2014

Solitary fibrous tumour of the pleura, also pleural solitary fibrous tumour, is a relatively common chest wall tumour.

The solitary fibrous tumour in general is dealt with in the solitary fibrous tumour article.

General

  • Uncommon overall.[1]
    • Common for the anatomical site.
  • Usually benign.
  • Slow growing.[1]
  • Elderly.
  • May be large - impair respiratory function.[2]

Gross/radiology

  • Chest wall.

Microscopic

Features:

  • Spindle cells - usually bland cytology.
  • Patternless pattern.
  • +/-Ropy collagen.

Suggestive of malignant:[2]

  • Mitotic rate >4/10 HPF.

DDx:

Images

  • Pleural SFT. (WC)

  • Pleural SFT. (WC)

  • Pleural SFT. (WC)

www:

IHC

Features:

  • CD34 +ve (19/23 cases[3]).
  • Ki-67 low (<5%).[2]
  • Vimentin +ve (23/23 cases[3]).
  • BCL2 +ve (23/23 cases[3]).
  • CD99 +ve (23/23 cases[3]).
  • SMA -ve/+ve (7 +ve/23 cases[3]).

Suggested stains:[citation needed]

  • CD34, CD99, BCL2, S-100, Ki-67.

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LEFT LUNG ("LARGE PLEURAL BASED MASS"), BIOPSY:
- SOLITARY FIBROUS TUMOUR.

Micro

The sections show cellular fibrous tissue with a patternless pattern. No mitotic activity is readily apparent. No significant nuclear atypia is identified. No necrosis is apparent.

See also

References

  1. ↑ 1.0 1.1 Mordenti, P.; Di Cicilia, R.; Delfanti, R.; Capelli, P.; Paties, C.; Cavanna, L.. "Solitary fibrous tumors of the pleura: a case report and review of the literature.". Tumori 99 (4): e177-83. doi:10.1700/1361.15120. PMID 24326857.
  2. ↑ 2.0 2.1 2.2 Abe, M.; Nomori, H.; Fukazawa, M.; Sugimura, H.; Narita, M.; Takeshi, A. (Oct 2013). "Giant Solitary Fibrous Tumor of the Pleura Causing Respiratory Insufficiency: Report of 3 Cases.". Ann Thorac Cardiovasc Surg. PMID 24088920.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Chen, HJ.; Zhang, HY.; Li, X.; Guo, LX.; Wei, B.; Guo, H.; Bu, H.; Yang, K. et al. (Sep 2004). "[Solitary fibrous tumor: the clinicopathologic and immunohistochemical characteristics of 26 cases].". Sichuan Da Xue Xue Bao Yi Xue Ban 35 (5): 675-9. PMID 15460417.
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