Difference between revisions of "Uterine adenomyosis"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Uterine adenomyosis -- intermed mag.jpg | |||
| Width = | |||
| Caption = Uterine adenomyosis. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = at least 2 of 3: (1) endometrial glands, (2) endometrial stroma, (3) hemosiderin-laden macrophages | |||
| Subtypes = | |||
| LMDDx = [[endometrioid endometrial carcinoma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = globoid shape, slightly enlarged, trabeculated cut surface +/- small foci of hemorrhage | |||
| Grossing = | |||
| Site = [[uterus]] | |||
| Assdx = [[endometriosis]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = cyclic pelvic pain | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Uterine adenomyosis''', also '''[[adenomyosis]] of the uterus''', is a relatively common benign pathology of the uterine corpus. It can be thought of as [[endometriosis]] in the uterine smooth muscle. | '''Uterine adenomyosis''', also '''[[adenomyosis]] of the uterus''', is a relatively common benign pathology of the uterine corpus. It can be thought of as [[endometriosis]] in the uterine smooth muscle. | ||
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DDx: | DDx: | ||
*[[Endometrioid endometrial carcinoma]]. | *[[Endometrioid endometrial carcinoma]]. | ||
===Images=== | |||
<gallery> | |||
Image: Uterine adenomyosis -- low mag.jpg | Adenomyosis - low mag. | |||
Image: Uterine adenomyosis -- intermed mag.jpg | Adenomyosis - intermed. mag. | |||
Image: Uterine adenomyosis -- high mag.jpg | Adenomyosis - high mag. | |||
Image: Uterine adenomyosis - alt -- high mag.jpg | Adenomyosis - high mag. | |||
Image: Uterine adenomyosis -- very high mag.jpg | Adenomyosis - very high mag. | |||
</gallery> | |||
==Sign out== | ==Sign out== | ||
Revision as of 03:20, 7 March 2014
| Uterine adenomyosis | |
|---|---|
| Diagnosis in short | |
 Uterine adenomyosis. H&E stain. | |
|
| |
| LM | at least 2 of 3: (1) endometrial glands, (2) endometrial stroma, (3) hemosiderin-laden macrophages |
| LM DDx | endometrioid endometrial carcinoma |
| Gross | globoid shape, slightly enlarged, trabeculated cut surface +/- small foci of hemorrhage |
| Site | uterus |
|
| |
| Associated Dx | endometriosis |
| Symptoms | cyclic pelvic pain |
| Prevalence | common |
| Prognosis | benign |
Uterine adenomyosis, also adenomyosis of the uterus, is a relatively common benign pathology of the uterine corpus. It can be thought of as endometriosis in the uterine smooth muscle.
Uterine adenomyoma redirects here.
General
- Common.
- May be a cause of bleeding.[1]
- Dysmenorrhea - painful menses.[2]
- Associated with endometriosis.[citation needed]
Gross
Features:
- Trabeculated cut surface +/- small foci of hemorrhage.[3]
- Often described as "basket-weave" pattern.
- Globoid, slightly enlarged.[4]
Note:
- May form a mass - known as adenomyoma.[5]
Image:
- Uterine adenomyosis (flickr.com/infopathic).
- Uterine adenomyosis - close-up (flickr.com/infopathic).
Microscopic
Features:
- Endometrial glands within uterine muscle - key feature.
- Endometrial glands:
- Circular.
- Simple epithelial or pseudostratified epithelium +/- mitoses.
- +/-Surrounded by endometrial stroma.
- Densely packed spindle cells without nuclear atypia.
- Blood:
- Within glands.
- Hemosiderin-laden macrophages.
- Endometrial glands:
Note:
- Can be thought of as endometriosis of the myometrium.
DDx:
Images
Adenomyosis - low mag.
Adenomyosis - intermed. mag.
Adenomyosis - high mag.
Adenomyosis - high mag.
Adenomyosis - very high mag.
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UTERUS, UTERINE CERVIX, TOTAL HYSTERECTOMY: - UTERUS WITH ADENOMYOSIS. - UTERINE CERVIX WITHIN NORMAL LIMITS. - PROLIFERATIVE PHASE ENDOMETRIUM.
UTERUS, UTERINE CERVIX, TOTAL HYSTERECTOMY: - UTERUS WITH SUPERFICIAL ADENOMYOSIS. - UTERINE CERVIX WITH PARTIAL DENUDATION, FOCUS OF ENDOMETRIOSIS AND INFLAMMATION, OTHERWISE WITHIN NORMAL LIMITS. - SUPERFICIAL FIBROSIS AND HYALINE CHANGE OF THE UTERINE LINING -- COMPATIBLE WITH PRIOR ABLATION.
See also
References
- ↑ Reinhold, C.; Tafazoli, F.; Mehio, A.; Wang, L.; Atri, M.; Siegelman, ES.; Rohoman, L. (Oct 1999). "Uterine adenomyosis: endovaginal US and MR imaging features with histopathologic correlation.". Radiographics 19 Spec No: S147-60. PMID 10517451.
- ↑ Cockerham, AZ.. "Adenomyosis: a challenge in clinical gynecology.". J Midwifery Womens Health 57 (3): 212-20. doi:10.1111/j.1542-2011.2011.00117.x. PMID 22594861.
- ↑ Lester, Susan Carole (2010). Manual of Surgical Pathology (3rd ed.). Saunders. pp. 432. ISBN 978-0-323-06516-0.
- ↑ HUNTER, WC.; SMITH, LL.; REINER, WC. (Apr 1947). "Uterine adenomyosis; incidence, symptoms, and pathology in 1,856 hysterectomies.". Am J Obstet Gynecol 53 (4): 663-8. PMID 20291238.
- ↑ Tahlan, A.; Nanda, A.; Mohan, H. (Oct 2006). "Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature.". Int J Gynecol Pathol 25 (4): 361-5. doi:10.1097/01.pgp.0000209570.08716.b3. PMID 16990713.