Difference between revisions of "Nuclear atypia"
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[[Image:Colorectal adenocarcinoma - alt -- high mag.jpg|thumb|right|200px|Nuclear atypia and [[stromal desmoplasia]] in [[colorectal adenocarcinoma]]. [[H&E stain]].]] | [[Image:Colorectal adenocarcinoma - alt -- high mag.jpg|thumb|right|200px|Nuclear atypia and [[stromal desmoplasia]] in a [[colorectal adenocarcinoma]]. [[H&E stain]].]] | ||
'''Nuclear atypia''', also '''atypical nuclei''', is an abnormal change of the cell nucleus. | '''Nuclear atypia''', also '''atypical nuclei''', is an abnormal change of the cell nucleus. | ||
Revision as of 19:29, 13 September 2014
Nuclear atypia, also atypical nuclei, is an abnormal change of the cell nucleus.
Nuclear atypia is often seen in malignancy; however, it may be seen in benign conditions - notably inflammation.
Cancer with no appreciable or minimal nuclear atypia
An incomplete list:
- Low grade papillary urothelial carcinoma.
- Some adenocarcinomas of the upper gastrointestinal tract, e.g. gallbladder adenocarcinoma, stomach adenocarcinoma, ductal adenocarcinoma of the pancreas.
- Invasive lobular carcinoma.
- Verrucous squamous cell carcinoma.
- Some malignant melanomas.