Difference between revisions of "TFEB-rearranged renal cell carcinoma"
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==Molecular== | ==Molecular== | ||
*t(6;11)(p21;q12) Alpha/TFEB.<ref name=Ref_WMSP281>{{Ref WMSP|281}}</ref> | *t(6;11)(p21;q12) Alpha/TFEB.<ref name=Ref_WMSP281>{{Ref WMSP|281}}</ref> | ||
==See also== | ==See also== | ||
*[[Kidney tumours]]. | *[[Kidney tumours]]. | ||
*[[Chromosomal translocations]]. | *[[Chromosomal translocations]]. | ||
*[[Pediatric pathology]]. | |||
==References== | ==References== | ||
Revision as of 23:11, 8 October 2014
Renal tumour with t(6;11) translocation, also t(6;11) renal cell carcinoma, is a rare kidney tumour seen primarily in children.
General
- Not common.
- Lymph node metastases are common.
- Essentially a pediatric tumour - case report of an adult.[1]
Microscopic
Features:
- Hyaline material between nests.
- Large cells with clear to eosinophilic cytoplasm.
Molecular
- t(6;11)(p21;q12) Alpha/TFEB.[2]
See also
References
- ↑ Ishihara, A.; Yamashita, Y.; Takamori, H.; Kuroda, N. (Sep 2011). "Renal carcinoma with (6;11)(p21;q12) translocation: Report of an adult case.". Pathol Int 61 (9): 539-45. doi:10.1111/j.1440-1827.2011.02711.x. PMID 21884304.
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 281. ISBN 978-0781765275.