Difference between revisions of "Renal angiomyoadenomatous tumour"
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==General== | ==General== | ||
*May be on a spectrum with [[clear cell papillary renal cell carcinoma]].<ref name=pmid23434146>{{Cite journal | last1 = Petersson | first1 = F. | last2 = Grossmann | first2 = P. | last3 = Hora | first3 = M. | last4 = Sperga | first4 = M. | last5 = Montiel | first5 = DP. | last6 = Martinek | first6 = P. | last7 = Gutierrez | first7 = ME. | last8 = Bulimbasic | first8 = S. | last9 = Michal | first9 = M. | title = Renal cell carcinoma with areas mimicking renal angiomyoadenomatous tumor/clear cell papillary renal cell carcinoma. | journal = Hum Pathol | volume = 44 | issue = 7 | pages = 1412-20 | month = Jul | year = 2013 | doi = 10.1016/j.humpath.2012.11.019 | PMID = 23434146 }}</ref> | *May be on a spectrum with [[clear cell papillary renal cell carcinoma]].<ref name=pmid23434146>{{Cite journal | last1 = Petersson | first1 = F. | last2 = Grossmann | first2 = P. | last3 = Hora | first3 = M. | last4 = Sperga | first4 = M. | last5 = Montiel | first5 = DP. | last6 = Martinek | first6 = P. | last7 = Gutierrez | first7 = ME. | last8 = Bulimbasic | first8 = S. | last9 = Michal | first9 = M. | title = Renal cell carcinoma with areas mimicking renal angiomyoadenomatous tumor/clear cell papillary renal cell carcinoma. | journal = Hum Pathol | volume = 44 | issue = 7 | pages = 1412-20 | month = Jul | year = 2013 | doi = 10.1016/j.humpath.2012.11.019 | PMID = 23434146 }}</ref> | ||
*First descried in 2000. | |||
Clincal: | |||
*Usually middle age (40s and 50s). | |||
==Gross== | |||
Features:<ref name=pmid22534244/> | |||
*Tan-brown renal mass +/-cystic component. | |||
==Microscopic== | |||
Features:<ref name=pmid22534244>{{Cite journal | last1 = Singh | first1 = C. | last2 = Kendi | first2 = AT. | last3 = Manivel | first3 = JC. | last4 = Pambuccian | first4 = SE. | title = Renal angiomyoadenomatous tumor. | journal = Ann Diagn Pathol | volume = 16 | issue = 6 | pages = 470-6 | month = Dec | year = 2012 | doi = 10.1016/j.anndiagpath.2012.01.006 | PMID = 22534244 }}</ref> | |||
*Leiomyomatous capsule of variable thickness - '''key feature'''. | |||
*Clear cell with basal nuclei and mild [[nuclear atypia]]. | |||
DDx:<ref name=pmid22534244/><ref>{{Cite journal | last1 = Petersson | first1 = F. | last2 = Branzovsky | first2 = J. | last3 = Martinek | first3 = P. | last4 = Korabecna | first4 = M. | last5 = Kruslin | first5 = B. | last6 = Hora | first6 = M. | last7 = Peckova | first7 = K. | last8 = Bauleth | first8 = K. | last9 = Pivovarcikova | first9 = K. | title = The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process. | journal = Virchows Arch | volume = 465 | issue = 1 | pages = 89-96 | month = Jul | year = 2014 | doi = 10.1007/s00428-014-1591-9 | PMID = 24838683 }}</ref> | |||
*[[Clear cell renal cell carcinoma]]. | |||
*[[Papillary renal cell carcinoma]]. | |||
*[[Angiomyolipoma]]. | |||
*[[Renal mixed epithelial and stromal tumour]]. | |||
==See also== | ==See also== |
Revision as of 01:31, 21 October 2014
Renal angiomyoadenomatous tumour, abbreviated RAT, is an uncommon kidney tumour not recognized by the WHO classification of renal neoplasia or the Vancouver modification.
General
- May be on a spectrum with clear cell papillary renal cell carcinoma.[1]
- First descried in 2000.
Clincal:
- Usually middle age (40s and 50s).
Gross
Features:[2]
- Tan-brown renal mass +/-cystic component.
Microscopic
Features:[2]
- Leiomyomatous capsule of variable thickness - key feature.
- Clear cell with basal nuclei and mild nuclear atypia.
- Clear cell renal cell carcinoma.
- Papillary renal cell carcinoma.
- Angiomyolipoma.
- Renal mixed epithelial and stromal tumour.
See also
References
- ↑ Petersson, F.; Grossmann, P.; Hora, M.; Sperga, M.; Montiel, DP.; Martinek, P.; Gutierrez, ME.; Bulimbasic, S. et al. (Jul 2013). "Renal cell carcinoma with areas mimicking renal angiomyoadenomatous tumor/clear cell papillary renal cell carcinoma.". Hum Pathol 44 (7): 1412-20. doi:10.1016/j.humpath.2012.11.019. PMID 23434146.
- ↑ 2.0 2.1 2.2 Singh, C.; Kendi, AT.; Manivel, JC.; Pambuccian, SE. (Dec 2012). "Renal angiomyoadenomatous tumor.". Ann Diagn Pathol 16 (6): 470-6. doi:10.1016/j.anndiagpath.2012.01.006. PMID 22534244.
- ↑ Petersson, F.; Branzovsky, J.; Martinek, P.; Korabecna, M.; Kruslin, B.; Hora, M.; Peckova, K.; Bauleth, K. et al. (Jul 2014). "The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process.". Virchows Arch 465 (1): 89-96. doi:10.1007/s00428-014-1591-9. PMID 24838683.