Difference between revisions of "Adenocarcinoma of the rete testis"
Jump to navigation
Jump to search
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Line 34: | Line 33: | ||
==General== | ==General== | ||
*Extremely rare - a few dozen cases in the world literature.<ref name=pmid3799821>{{Cite journal | last1 = Newbold | first1 = RR. | last2 = Bullock | first2 = BC. | last3 = McLachlan | first3 = JA. | title = Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. | journal = Am J Pathol | volume = 125 | issue = 3 | pages = 625-8 | month = Dec | year = 1986 | doi = | PMID = 3799821 | PMC = 1888460 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/?page=1}}</ref | *Extremely rare<ref name=pmid6465420>{{Cite journal | last1 = Nochomovitz | first1 = LE. | last2 = Orenstein | first2 = JM. | title = Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates. | journal = Am J Surg Pathol | volume = 8 | issue = 8 | pages = 625-34 | month = Aug | year = 1984 | doi = | PMID = 6465420 }}</ref> - a few dozen cases in the world literature. | ||
*Typically older men (>60 years old), but reported in younger men with undescended testis.<ref name=pmid6465420/> | |||
*Possible association of diethylstilbestrol.<ref name=pmid3799821>{{Cite journal | last1 = Newbold | first1 = RR. | last2 = Bullock | first2 = BC. | last3 = McLachlan | first3 = JA. | title = Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. | journal = Am J Pathol | volume = 125 | issue = 3 | pages = 625-8 | month = Dec | year = 1986 | doi = | PMID = 3799821 | PMC = 1888460 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/?page=1}}</ref> | |||
*Prognosis poor<ref name=pmid17853037>{{Cite journal | last1 = Sogni | first1 = F. | last2 = Monga | first2 = G. | last3 = Terrone | first3 = C. | last4 = Gontero | first4 = P. | title = Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. | journal = Scand J Urol Nephrol | volume = 42 | issue = 1 | pages = 83-5 | month = | year = 2008 | doi = 10.1080/00365590701517608 | PMID = 17853037 }}</ref> - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.<ref name=pmid7571213>{{Cite journal | last1 = Sánchez-Chapado | first1 = M. | last2 = Angulo | first2 = JC. | last3 = Haas | first3 = GP. | title = Adenocarcinoma of the rete testis. | journal = Urology | volume = 46 | issue = 4 | pages = 468-75 | month = Oct | year = 1995 | doi = 10.1016/S0090-4295(99)80257-X | PMID = 7571213 }}</ref> | *Prognosis poor<ref name=pmid17853037>{{Cite journal | last1 = Sogni | first1 = F. | last2 = Monga | first2 = G. | last3 = Terrone | first3 = C. | last4 = Gontero | first4 = P. | title = Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. | journal = Scand J Urol Nephrol | volume = 42 | issue = 1 | pages = 83-5 | month = | year = 2008 | doi = 10.1080/00365590701517608 | PMID = 17853037 }}</ref> - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.<ref name=pmid7571213>{{Cite journal | last1 = Sánchez-Chapado | first1 = M. | last2 = Angulo | first2 = JC. | last3 = Haas | first3 = GP. | title = Adenocarcinoma of the rete testis. | journal = Urology | volume = 46 | issue = 4 | pages = 468-75 | month = Oct | year = 1995 | doi = 10.1016/S0090-4295(99)80257-X | PMID = 7571213 }}</ref> | ||
==Gross== | |||
*Lesion of the testicular hilum.<ref name=pmid6465420/> | |||
==Microscopic== | ==Microscopic== | ||
| Line 42: | Line 45: | ||
*Adenocarcinoma: | *Adenocarcinoma: | ||
**Tubular or papillary architecture.<ref name=pmid3799821/> | **Tubular or papillary architecture.<ref name=pmid3799821/> | ||
**Columnar cells with cigar-shaped nuclei. | **Columnar or cuboidal cells, often with cigar-shaped nuclei. | ||
*Transistion to normal appearing rete testis.<ref name=pmid6465420/> | |||
DDx: | DDx: | ||
| Line 48: | Line 52: | ||
*[[Metastatic]] carcinoma involving the testis - usually [[prostate carcinoma|prostate]], kidney, or colon.<ref name=pmid18769334>{{Cite journal | last1 = Ulbright | first1 = TM. | last2 = Young | first2 = RH. | title = Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. | journal = Am J Surg Pathol | volume = 32 | issue = 11 | pages = 1683-93 | month = Nov | year = 2008 | doi = 10.1097/PAS.0b013e3181788516 | PMID = 18769334 }}</ref> | *[[Metastatic]] carcinoma involving the testis - usually [[prostate carcinoma|prostate]], kidney, or colon.<ref name=pmid18769334>{{Cite journal | last1 = Ulbright | first1 = TM. | last2 = Young | first2 = RH. | title = Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. | journal = Am J Surg Pathol | volume = 32 | issue = 11 | pages = 1683-93 | month = Nov | year = 2008 | doi = 10.1097/PAS.0b013e3181788516 | PMID = 18769334 }}</ref> | ||
*[[Sertoli cell tumour]]. | *[[Sertoli cell tumour]]. | ||
*[[Malignant mesothelioma]].<ref name=pmid6465420/> | |||
===Images=== | ===Images=== | ||
Revision as of 06:52, 16 December 2014
| Adenocarcinoma of the rete testis | |
|---|---|
| Diagnosis in short | |
 Adenocarcinoma of the rete testis. H&E stain. | |
| LM DDx | adenomatous hyperplasia of the rete testis, Sertoli cell tumour, metastasis |
| Gross | orchiectomy grossing |
| Site | testis - specifically rete testis |
|
| |
| Prevalence | extremely rare |
| Prognosis | poor |
| Clin. DDx | other testicular mass |
Adenocarcinoma of the rete testis, also rete testis adenocarcinoma, is a very rare malignant tumour of the testis.
General
- Extremely rare[1] - a few dozen cases in the world literature.
- Typically older men (>60 years old), but reported in younger men with undescended testis.[1]
- Possible association of diethylstilbestrol.[2]
- Prognosis poor[3] - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.[4]
Gross
- Lesion of the testicular hilum.[1]
Microscopic
Features:
- Adenocarcinoma:
- Tubular or papillary architecture.[2]
- Columnar or cuboidal cells, often with cigar-shaped nuclei.
- Transistion to normal appearing rete testis.[1]
DDx:
- Adenomatous hyperplasia of the rete testis.
- Metastatic carcinoma involving the testis - usually prostate, kidney, or colon.[5]
- Sertoli cell tumour.
- Malignant mesothelioma.[1]
Images
ART - low mag. (WC)
ART - intermed. mag. (WC)
ART - high mag. (WC)
ART - high mag. (WC)
ART - very high mag. (WC)
www:
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Nochomovitz, LE.; Orenstein, JM. (Aug 1984). "Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates.". Am J Surg Pathol 8 (8): 625-34. PMID 6465420.
- ↑ 2.0 2.1 Newbold, RR.; Bullock, BC.; McLachlan, JA. (Dec 1986). "Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.". Am J Pathol 125 (3): 625-8. PMC 1888460. PMID 3799821. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/.
- ↑ Sogni, F.; Monga, G.; Terrone, C.; Gontero, P. (2008). "Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas.". Scand J Urol Nephrol 42 (1): 83-5. doi:10.1080/00365590701517608. PMID 17853037.
- ↑ Sánchez-Chapado, M.; Angulo, JC.; Haas, GP. (Oct 1995). "Adenocarcinoma of the rete testis.". Urology 46 (4): 468-75. doi:10.1016/S0090-4295(99)80257-X. PMID 7571213.
- ↑ Ulbright, TM.; Young, RH. (Nov 2008). "Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features.". Am J Surg Pathol 32 (11): 1683-93. doi:10.1097/PAS.0b013e3181788516. PMID 18769334.
- ↑ Yang, Z.; Sheng, C.; Cao, L.; Wang, D.. "Adenocarcinoma of rete testis with widespread liver metastasis.". Can Urol Assoc J 7 (9-10): E654-6. doi:10.5489/cuaj.470. PMID 24409217.
- ↑ Tian, Y.; Yao, W.; Yang, L.; Wang, J.; Wazir, R.; Wang, K. (Feb 2014). "Primary adenocarcinoma of the rete testis: A case report and review of the literature.". Oncol Lett 7 (2): 455-457. doi:10.3892/ol.2013.1708. PMID 24396468.
- ↑ Wu, CA.; Chen, YH.; Man, KM.; Shen, JL.; Chen, WC. (2011). "Papillary adenocarcinoma of rete testis mimics inflammatory lump: a case report.". Case Rep Urol 2011: 857812. doi:10.1155/2011/857812. PMID 22606627.