Difference between revisions of "Adenocarcinoma of the rete testis"

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*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881943/figure/f2-ol-07-02-0455/ ART (nih.gov)].<ref name=pmid24396468>{{Cite journal  | last1 = Tian | first1 = Y. | last2 = Yao | first2 = W. | last3 = Yang | first3 = L. | last4 = Wang | first4 = J. | last5 = Wazir | first5 = R. | last6 = Wang | first6 = K. | title = Primary adenocarcinoma of the rete testis: A case report and review of the literature. | journal = Oncol Lett | volume = 7 | issue = 2 | pages = 455-457 | month = Feb | year = 2014 | doi = 10.3892/ol.2013.1708 | PMID = 24396468 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881943/figure/f2-ol-07-02-0455/ ART (nih.gov)].<ref name=pmid24396468>{{Cite journal  | last1 = Tian | first1 = Y. | last2 = Yao | first2 = W. | last3 = Yang | first3 = L. | last4 = Wang | first4 = J. | last5 = Wazir | first5 = R. | last6 = Wang | first6 = K. | title = Primary adenocarcinoma of the rete testis: A case report and review of the literature. | journal = Oncol Lett | volume = 7 | issue = 2 | pages = 455-457 | month = Feb | year = 2014 | doi = 10.3892/ol.2013.1708 | PMID = 24396468 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350189/figure/fig3/ ART (nih.gov)].<ref>{{Cite journal  | last1 = Wu | first1 = CA. | last2 = Chen | first2 = YH. | last3 = Man | first3 = KM. | last4 = Shen | first4 = JL. | last5 = Chen | first5 = WC. | title = Papillary adenocarcinoma of rete testis mimics inflammatory lump: a case report. | journal = Case Rep Urol | volume = 2011 | issue =  | pages = 857812 | month =  | year = 2011 | doi = 10.1155/2011/857812 | PMID = 22606627 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350189/figure/fig3/ ART (nih.gov)].<ref>{{Cite journal  | last1 = Wu | first1 = CA. | last2 = Chen | first2 = YH. | last3 = Man | first3 = KM. | last4 = Shen | first4 = JL. | last5 = Chen | first5 = WC. | title = Papillary adenocarcinoma of rete testis mimics inflammatory lump: a case report. | journal = Case Rep Urol | volume = 2011 | issue =  | pages = 857812 | month =  | year = 2011 | doi = 10.1155/2011/857812 | PMID = 22606627 }}</ref>
==IHC==
Features:<ref name=pmid23800084/>
*CK7 +ve.
*EMA +ve.
Others:<ref name=pmid23800084/>
*AFP -ve.
*CD30 -ve.
*PLAP -ve.
*CK5/6 -ve.
*Calretinin -ve.
*PSA -ve.


==See also==
==See also==
Line 72: Line 85:


==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Testis]]
[[Category:Testis]]

Revision as of 06:59, 16 December 2014

Adenocarcinoma of the rete testis
Diagnosis in short

Adenocarcinoma of the rete testis. H&E stain.
LM DDx adenomatous hyperplasia of the rete testis, Sertoli cell tumour, metastasis
Gross orchiectomy grossing
Site testis - specifically rete testis
Prevalence extremely rare
Prognosis poor
Clin. DDx other testicular mass

Adenocarcinoma of the rete testis, also rete testis adenocarcinoma, is a very rare malignant tumour of the testis.

General

  • Extremely rare[1] - a few dozen cases in the world literature.
  • Typically older men (>60 years old), but reported in younger men with undescended testis.[1]
  • Possible association of diethylstilbestrol.[2]
  • Prognosis poor[3] - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.[4]

Gross

  • Lesion of the testicular hilum.[1]

Microscopic

Features:

  • Adenocarcinoma:
    • Atypical columnar or cuboidal cells, often with cigar-shaped nuclei.
    • Tubular or papillary architecture.[2]
  • Transistion to normal appearing rete testis.[1]

DDx:

Images

  • ART - low mag. (WC)

  • ART - intermed. mag. (WC)

  • ART - high mag. (WC)

  • ART - high mag. (WC)

  • ART - very high mag. (WC)

www:

IHC

Features:[5]

  • CK7 +ve.
  • EMA +ve.

Others:[5]

  • AFP -ve.
  • CD30 -ve.
  • PLAP -ve.
  • CK5/6 -ve.
  • Calretinin -ve.
  • PSA -ve.

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Nochomovitz, LE.; Orenstein, JM. (Aug 1984). "Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates.". Am J Surg Pathol 8 (8): 625-34. PMID 6465420.
  2. ↑ 2.0 2.1 Newbold, RR.; Bullock, BC.; McLachlan, JA. (Dec 1986). "Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.". Am J Pathol 125 (3): 625-8. PMC 1888460. PMID 3799821. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/.
  3. ↑ Sogni, F.; Monga, G.; Terrone, C.; Gontero, P. (2008). "Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas.". Scand J Urol Nephrol 42 (1): 83-5. doi:10.1080/00365590701517608. PMID 17853037.
  4. ↑ Sánchez-Chapado, M.; Angulo, JC.; Haas, GP. (Oct 1995). "Adenocarcinoma of the rete testis.". Urology 46 (4): 468-75. doi:10.1016/S0090-4295(99)80257-X. PMID 7571213.
  5. ↑ 5.0 5.1 5.2 Lin, XY.; Yu, JH.; Xu, HT.; Wang, L.; Fan, CF.; Liu, Y.; Wang, EH. (2013). "A case of adenocarcinoma of the rete testis accompanied by focal adenomatous hyperplasia.". Diagn Pathol 8: 105. doi:10.1186/1746-1596-8-105. PMID 23800084.
  6. ↑ Ulbright, TM.; Young, RH. (Nov 2008). "Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features.". Am J Surg Pathol 32 (11): 1683-93. doi:10.1097/PAS.0b013e3181788516. PMID 18769334.
  7. ↑ Yang, Z.; Sheng, C.; Cao, L.; Wang, D.. "Adenocarcinoma of rete testis with widespread liver metastasis.". Can Urol Assoc J 7 (9-10): E654-6. doi:10.5489/cuaj.470. PMID 24409217.
  8. ↑ Tian, Y.; Yao, W.; Yang, L.; Wang, J.; Wazir, R.; Wang, K. (Feb 2014). "Primary adenocarcinoma of the rete testis: A case report and review of the literature.". Oncol Lett 7 (2): 455-457. doi:10.3892/ol.2013.1708. PMID 24396468.
  9. ↑ Wu, CA.; Chen, YH.; Man, KM.; Shen, JL.; Chen, WC. (2011). "Papillary adenocarcinoma of rete testis mimics inflammatory lump: a case report.". Case Rep Urol 2011: 857812. doi:10.1155/2011/857812. PMID 22606627.
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