Difference between revisions of "Well-differentiated papillary mesothelioma"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      =
| Width      =
| Caption    =
| Synonyms  = benign papillary mesothelioma
| Micro      = papillary structures with thick fibrous cores and simple cuboidal epithelium, lacks cytologic atypia
| Subtypes  =
| LMDDx      = [[ovarian serous carcinoma]], [[serous borderline tumour of the ovary]], [[malignant mesothelioma]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[pleura]], [[peritoneum]], tunica vaginalis ([[testis]])
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = rare
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = typical indolent
| Other      =
| ClinDDx    = [[tuberculosis]], [[carcinoma|carcinomatosis]], [[primary peritoneal serous carcinoma]]
| Tx        =
}}
'''Well-differentiated papillary mesothelioma''', abbreviated '''WDPM''', is a rare type of [[mesothelioma]] that typically has an indolent behaviour.<ref name=pmid11688466>{{Cite journal  | last1 = Butnor | first1 = KJ. | last2 = Sporn | first2 = TA. | last3 = Hammar | first3 = SP. | last4 = Roggli | first4 = VL. | title = Well-differentiated papillary mesothelioma. | journal = Am J Surg Pathol | volume = 25 | issue = 10 | pages = 1304-9 | month = Oct | year = 2001 | doi =  | PMID = 11688466 }}</ref>
'''Well-differentiated papillary mesothelioma''', abbreviated '''WDPM''', is a rare type of [[mesothelioma]] that typically has an indolent behaviour.<ref name=pmid11688466>{{Cite journal  | last1 = Butnor | first1 = KJ. | last2 = Sporn | first2 = TA. | last3 = Hammar | first3 = SP. | last4 = Roggli | first4 = VL. | title = Well-differentiated papillary mesothelioma. | journal = Am J Surg Pathol | volume = 25 | issue = 10 | pages = 1304-9 | month = Oct | year = 2001 | doi =  | PMID = 11688466 }}</ref>


Revision as of 07:40, 8 March 2015

Well-differentiated papillary mesothelioma
Diagnosis in short
Synonyms benign papillary mesothelioma
LM papillary structures with thick fibrous cores and simple cuboidal epithelium, lacks cytologic atypia
LM DDx ovarian serous carcinoma, serous borderline tumour of the ovary, malignant mesothelioma
Site pleura, peritoneum, tunica vaginalis (testis)
Prevalence rare
Prognosis typical indolent
Clin. DDx tuberculosis, carcinomatosis, primary peritoneal serous carcinoma

Well-differentiated papillary mesothelioma, abbreviated WDPM, is a rare type of mesothelioma that typically has an indolent behaviour.[1]

It is also known as benign papillary mesothelioma. It should not be confused with malignant mesothelioma or benign multicystic mesothelioma.

General

  • Benign.
    • Some say it is borderline.[2]
  • Classically women of reproductive age.[3]
  • Reported in tunica vaginalis of the testis.[4]
  • Associated with asbestos exposure.[1]

Gross

Features - typical:

  • Multiple peritoneal nodules.
  • Ascites.

DDx:[3]

Microscopic

Features:

  • Papillary structures with:
    • Thick fibrous cores.
    • Simple cuboidal epithelium.
      • Small nucleoli.

Note:

  • Lack cytologic atypia.

DDx:[5]

Images

www:

See also

References

  1. ↑ 1.0 1.1 Butnor, KJ.; Sporn, TA.; Hammar, SP.; Roggli, VL. (Oct 2001). "Well-differentiated papillary mesothelioma.". Am J Surg Pathol 25 (10): 1304-9. PMID 11688466.
  2. ↑ Bürrig, KF.; Pfitzer, P.; Hort, W. (1990). "Well-differentiated papillary mesothelioma of the peritoneum: a borderline mesothelioma. Report of two cases and review of literature.". Virchows Arch A Pathol Anat Histopathol 417 (5): 443-7. PMID 2122588.
  3. ↑ 3.0 3.1 Park, JY.; Kim, KW.; Kwon, HJ.; Park, MS.; Kwon, GY.; Jun, SY.; Yu, ES. (Sep 2008). "Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis.". AJR Am J Roentgenol 191 (3): 814-25. doi:10.2214/AJR.07.3628. PMID 18716115.
  4. ↑ Chetty, R. (Nov 1992). "Well differentiated (benign) papillary mesothelioma of the tunica vaginalis.". J Clin Pathol 45 (11): 1029-30. PMID 1452778.
  5. ↑ Truong, LD.; Maccato, ML.; Awalt, H.; Cagle, PT.; Schwartz, MR.; Kaplan, AL. (Jan 1990). "Serous surface carcinoma of the peritoneum: a clinicopathologic study of 22 cases.". Hum Pathol 21 (1): 99-110. PMID 1688545.
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