Difference between revisions of "Hereditary diffuse gastric cancer"
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[[Image:Signet_ring_cell_carcinoma_-_very_high_mag.jpg|thumb|right|200px|[[Signet ring cell carcinoma]], as may be seen in hereditary diffuse gastric cancer. [[H&E stain]].]] | |||
'''Hereditary diffuse gastric cancer''', abbreviated '''HDGC''', is an important hereditary cause of diffuse [[gastric cancer]].<ref>{{cite journal |author=Sereno M, Aguayo C, Guillén Ponce C, ''et al.'' |title=Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention |journal=Clin Transl Oncol |volume=13 |issue=9 |pages=599–610 |year=2011 |month=September |pmid=21865131 |doi= |url=}}</ref> | '''Hereditary diffuse gastric cancer''', abbreviated '''HDGC''', is an important hereditary cause of diffuse [[gastric cancer]].<ref>{{cite journal |author=Sereno M, Aguayo C, Guillén Ponce C, ''et al.'' |title=Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention |journal=Clin Transl Oncol |volume=13 |issue=9 |pages=599–610 |year=2011 |month=September |pmid=21865131 |doi= |url=}}</ref> | ||
Revision as of 18:07, 26 May 2015
Hereditary diffuse gastric cancer, abbreviated HDGC, is an important hereditary cause of diffuse gastric cancer.[1]
It is caused by mutations in the epithelial cadherin gene (also E-cadherin and CDH1).[2][3]
General
It is associated with:
See also
References
- ↑ Sereno M, Aguayo C, Guillén Ponce C, et al. (September 2011). "Gastric tumours in hereditary cancer syndromes: clinical features, molecular biology and strategies for prevention". Clin Transl Oncol 13 (9): 599–610. PMID 21865131.
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 137215
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 192090