Difference between revisions of "Auer rod"
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[[Image:Auer_Rods_in_Leukemic_Blast_(2434847298).jpg | thumb | Micrograph showing an Auer rod in a blast. [[Wright stain]]. (WC)]] | [[Image:Auer_Rods_in_Leukemic_Blast_(2434847298).jpg | thumb | Micrograph showing an Auer rod in a blast. [[Wright stain]]. (WC)]] | ||
'''Auer rod''' a microscopic finding typical of some types of [[acute myeloid leukemia]] and seen in [[myelodysplastic | '''Auer rod''' a microscopic finding typical of some types of [[acute myeloid leukemia]] and seen in [[myelodysplastic syndromes]]. | ||
It may be referred to as an '''Auer body'''. | It may be referred to as an '''Auer body'''. | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Needle-like cytoplasmic bodies.<ref name=pmid15434012>{{Cite journal | last1 = ACKERMAN | first1 = GA. | title = Microscopic and histochemical studies on the Auer bodies in leukemic cells. | journal = Blood | volume = 5 | issue = 9 | pages = 847-63 | month = Sep | year = 1950 | doi = | PMID = 15434012 }}</ref> | *Needle-like cytoplasmic bodies - classic appearance.<ref name=pmid15434012>{{Cite journal | last1 = ACKERMAN | first1 = GA. | title = Microscopic and histochemical studies on the Auer bodies in leukemic cells. | journal = Blood | volume = 5 | issue = 9 | pages = 847-63 | month = Sep | year = 1950 | doi = | PMID = 15434012 }}</ref> | ||
**Other shapes: comma-like, diamond-like, rectangular, rarely glandular or corkscrew-like. | |||
DDx: | DDx: | ||
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==See als== | ==See als== | ||
*[[Acute myeloid leukemia]]. | *[[Acute myeloid leukemia]]. | ||
*[[Russell bodies]]. | |||
==References== | ==References== | ||
Latest revision as of 00:06, 28 July 2015
.jpg)
Micrograph showing an Auer rod in a blast. Wright stain. (WC)
Auer rod a microscopic finding typical of some types of acute myeloid leukemia and seen in myelodysplastic syndromes.
It may be referred to as an Auer body.
General
Microscopic
Features:
- Needle-like cytoplasmic bodies - classic appearance.[3]
- Other shapes: comma-like, diamond-like, rectangular, rarely glandular or corkscrew-like.
DDx:
- Auer-rod like inclusions - may be seen in multiple myeloma[4] or lymphoma cells.[2]
Images
Auer rods. (WC)
Abundant Auer rods in a Faggot cell. (WC)
See als
References
- ↑ Yoshida, Y.; Oguma, S.; Ohno, H.; Auer, J. (May 2009). "John Auer and Auer rods; controversies revisited.". Leuk Res 33 (5): 614-6. doi:10.1016/j.leukres.2008.09.014. PMID 18947869.
- ↑ 2.0 2.1 Groom, DA.; Wong, D.; Brynes, RK.; Macaulay, LK. (Jul 1991). "Auer rod-like inclusions in circulating lymphoma cells.". Am J Clin Pathol 96 (1): 111-5. PMID 1712539.
- ↑ ACKERMAN, GA. (Sep 1950). "Microscopic and histochemical studies on the Auer bodies in leukemic cells.". Blood 5 (9): 847-63. PMID 15434012.
- ↑ Abdulsalam, AH.; Bain, BJ. (Mar 2014). "Auer-rod like inclusions in multiple myeloma.". Am J Hematol 89 (3): 338. doi:10.1002/ajh.23648. PMID 24338920.