Difference between revisions of "Thyroid transcription factor-1"

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[[Image:Lung_adenocarcinoma_-_TTF-1_-_high_mag.jpg|thumb|right|250px|TTF-1 staining in [[lung adenocarcinoma]].]]
{{ Infobox immunostain
| Name      = {{PAGENAME}}
| Image     = Lung_adenocarcinoma_-_TTF-1_-_high_mag.jpg
| Width      =
| Caption    = TTF-1 staining in [[lung adenocarcinoma]]. (WC)
| Abbrev    =
| Synonyms  =
| Similar    =
| Clones    =     
| Use        =
| Subspecial = 
| Pattern    = nuclear staining
| Positive  = [[adenocarcinoma of the lung]], [[small cell carcinoma of the lung]], thyroid, [[hepatocellular carcinoma]] (cytoplasmic staining)
| Negative  = [[squamous cell carcinoma of the lung]]
| Other      =
}}
'''Thyroid transcription factor-1''', abbreviated '''TTF-1''' is a transcription factor seen in lung and thyroid.<ref>{{Cite journal  | last1 = Ordóñez | first1 = NG. | title = Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas. | journal = Adv Anat Pathol | volume = 7 | issue = 2 | pages = 123-7 | month = Mar | year = 2000 | doi =  | PMID = 10721419 }}</ref>
'''Thyroid transcription factor-1''', abbreviated '''TTF-1''' is a transcription factor seen in lung and thyroid.<ref>{{Cite journal  | last1 = Ordóñez | first1 = NG. | title = Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas. | journal = Adv Anat Pathol | volume = 7 | issue = 2 | pages = 123-7 | month = Mar | year = 2000 | doi =  | PMID = 10721419 }}</ref>


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==Tumours==
==Tumours==
*[[Lung adenocarcinoma]].<ref>{{Cite journal  | last1 = Yatabe | first1 = Y. | last2 = Mitsudomi | first2 = T. | last3 = Takahashi | first3 = T. | title = TTF-1 expression in pulmonary adenocarcinomas. | journal = Am J Surg Pathol | volume = 26 | issue = 6 | pages = 767-73 | month = Jun | year = 2002 | doi =  | PMID = 12023581 }}</ref>
*[[Lung adenocarcinoma]].<ref name=pmid12023581>{{Cite journal  | last1 = Yatabe | first1 = Y. | last2 = Mitsudomi | first2 = T. | last3 = Takahashi | first3 = T. | title = TTF-1 expression in pulmonary adenocarcinomas. | journal = Am J Surg Pathol | volume = 26 | issue = 6 | pages = 767-73 | month = Jun | year = 2002 | doi =  | PMID = 12023581 }}</ref>
*[[Small cell carcinoma of the lung]].
*[[Small cell carcinoma of the lung]].


Revision as of 00:41, 25 September 2015

Thyroid transcription factor-1
Immunostain in short

TTF-1 staining in lung adenocarcinoma. (WC)
Normal staining pattern nuclear staining
Positive adenocarcinoma of the lung, small cell carcinoma of the lung, thyroid, hepatocellular carcinoma (cytoplasmic staining)
Negative squamous cell carcinoma of the lung

Thyroid transcription factor-1, abbreviated TTF-1 is a transcription factor seen in lung and thyroid.[1]

Positive staining

  • Nuclear staining.

Normal tissues

Tumours

Negative

Negative staining:

See also

References

  1. ↑ Ordóñez, NG. (Mar 2000). "Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas.". Adv Anat Pathol 7 (2): 123-7. PMID 10721419.
  2. ↑ Yatabe, Y.; Mitsudomi, T.; Takahashi, T. (Jun 2002). "TTF-1 expression in pulmonary adenocarcinomas.". Am J Surg Pathol 26 (6): 767-73. PMID 12023581.
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