Difference between revisions of "Glypican 3"
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*[[Squamous cell carcinoma of the lung]].<ref name=pmid25896897/> | *[[Squamous cell carcinoma of the lung]].<ref name=pmid25896897/> | ||
*[[Yolk sac tumour]]. | *[[Yolk sac tumour]]. | ||
**More sensitive than [[alpha-fetoprotein]] (AFP).<ref name=pmid20438407>{{Cite journal | last1 = Emerson | first1 = RE. | last2 = Ulbright | first2 = TM. | title = Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers. | journal = Pathology | volume = 42 | issue = 4 | pages = 344-55 | month = Jun | year = 2010 | doi = 10.3109/00313021003767355 | PMID = 20438407 }}</ref> | |||
===Images=== | ===Images=== | ||
Revision as of 00:55, 30 September 2015
Glypican 3, abbreviated GPC3,[1] is a common immunostain used in gastrointestinal pathology and genitourinary pathology.
Positive
- Hepatocellular carcinoma.[2]
- Malignant melanoma.[2]
- Squamous cell carcinoma of the lung.[2]
- Yolk sac tumour.
- More sensitive than alpha-fetoprotein (AFP).[3]
Images
See also
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 300037
- ↑ 2.0 2.1 2.2 2.3 Aydin, O.; Yildiz, L.; Baris, S.; Dundar, C.; Karagoz, F. (2015). "Expression of Glypican 3 in low and high grade urothelial carcinomas.". Diagn Pathol 10: 34. doi:10.1186/s13000-015-0266-4. PMID 25896897.
- ↑ Emerson, RE.; Ulbright, TM. (Jun 2010). "Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers.". Pathology 42 (4): 344-55. doi:10.3109/00313021003767355. PMID 20438407.