Difference between revisions of "CD99"
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| Line 7: | Line 7: | ||
*[[Angiomatoid fibrous histiocytoma]]. | *[[Angiomatoid fibrous histiocytoma]]. | ||
*[[Desmoplastic small round cell tumour]]. | *[[Desmoplastic small round cell tumour]]. | ||
===Weak/cytoplasmic staining=== | |||
*[[Synovial sarcoma]]. | |||
*[[Rhabdomyosarcoma]]. | |||
*[[Rhabdoid tumour]]. | |||
===Others=== | ===Others=== | ||
Latest revision as of 12:40, 15 October 2015
CD99 is a commonly available immunostain with various uses. It stains a lot of different tumour and has been described by one soft tissue pathologist as slutty.
Positive
Membrane staining
- Ewing sarcoma - diffuse (plasma membrane) staining.
- Lymphoblastic lymphoma/leukemia.
- Angiomatoid fibrous histiocytoma.
- Desmoplastic small round cell tumour.
Weak/cytoplasmic staining
Others
- Malignant melanoma (9 of 10 cases[1]).
- Atypical fibroxanthoma (19 of 26 cases[1]).
Negative
- Squamous cell carcinoma.[1]
- Undifferentiated small round cell sarcoma with t(4;19) (CIC-DUX sarcoma) - negative or weak positive.