Difference between revisions of "Medial calcific sclerosis"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Medial calcific sclerosis -- intermed mag.jpg | |||
| Width = | |||
| Caption = Medial calcific sclerosis. [[H&E stain]]. | |||
| Synonyms = Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, Mönckeberg's arteriosclerosis (also written ''Monckeberg's arteriosclerosis'') | |||
| Micro = calcifications of the tunica media | |||
| Subtypes = | |||
| LMDDx = [[atherosclerosis]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[blood vessels]] - arteries | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = good | |||
| Other = | |||
| ClinDDx = | |||
| Tx = (nothing) | |||
}} | |||
'''Medial calcific sclerosis''' is a type of arteriosclerosis that has no significant clinical impact. | |||
It is also known as '''Moenckeberg medial calcific sclerosis''', '''calcific medial sclerosis of Monckeberg''', and '''Mönckeberg's arteriosclerosis''' (also written '''Monckeberg's arteriosclerosis'''). | |||
==General== | |||
*Usually of no clinical consequence. | |||
==Microscopic== | |||
Features:<ref name=Ref_Klatt7>{{Ref Klatt|7}}</ref> | |||
*Medial calcification (purple irregular stuff on [[H&E stain|H&E]] -- calcium phosphate). | |||
Note: | |||
*Lumen unaffected. | |||
DDx: | |||
*[[Atherosclerosis]] (severe) - intimal hyperplasia with stenosis, calcifications typically in tunica intima. | |||
===Images=== | |||
<gallery> | |||
Image: Medial calcific sclerosis -- low mag.jpg | MCS - low mag. (WC) | |||
Image: Medial calcific sclerosis -- intermed mag.jpg | MCS - intermed. mag. (WC) | |||
Image: Medial calcific sclerosis -- high mag.jpg | MCS - high mag. (WC) | |||
Image: Medial calcific sclerosis - alt -- intermed mag.jpg | MCS - intermed. mag. (WC) | |||
Image: Medial calcific sclerosis - alt -- high mag.jpg | MCS - high mag. (WC) | |||
</gallery> | |||
<gallery> | |||
Image:Calcificatio_atherosclerotica.jpg | MCS. (WC) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
RIGHT LEG, BELOW KNEE AMPUTATION: | |||
- MINIMAL-TO-MILD LARGE VESSEL ATHEROSCLEROSIS, SEE COMMENT. | |||
- MEDIAL CALCIFIC SCLEROSIS. | |||
- SKIN WITH DERMAL FIBROSIS. | |||
COMMENT: | |||
The sections may not be representative of disease in the distal vascular bed. | |||
</pre> | |||
==See also== | |||
*[[Vascular disease]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Cardiovascular pathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Latest revision as of 20:18, 10 March 2016
| Medial calcific sclerosis | |
|---|---|
| Diagnosis in short | |
 Medial calcific sclerosis. H&E stain. | |
|
| |
| Synonyms | Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, Mönckeberg's arteriosclerosis (also written Monckeberg's arteriosclerosis) |
|
| |
| LM | calcifications of the tunica media |
| LM DDx | atherosclerosis |
| Site | blood vessels - arteries |
|
| |
| Prognosis | good |
| Treatment | (nothing) |
Medial calcific sclerosis is a type of arteriosclerosis that has no significant clinical impact.
It is also known as Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, and Mönckeberg's arteriosclerosis (also written Monckeberg's arteriosclerosis).
General
- Usually of no clinical consequence.
Microscopic
Features:[1]
- Medial calcification (purple irregular stuff on H&E -- calcium phosphate).
Note:
- Lumen unaffected.
DDx:
- Atherosclerosis (severe) - intimal hyperplasia with stenosis, calcifications typically in tunica intima.
Images
MCS - low mag. (WC)
MCS - intermed. mag. (WC)
MCS - high mag. (WC)
MCS - intermed. mag. (WC)
MCS - high mag. (WC)
MCS. (WC)
Sign out
RIGHT LEG, BELOW KNEE AMPUTATION: - MINIMAL-TO-MILD LARGE VESSEL ATHEROSCLEROSIS, SEE COMMENT. - MEDIAL CALCIFIC SCLEROSIS. - SKIN WITH DERMAL FIBROSIS. COMMENT: The sections may not be representative of disease in the distal vascular bed.
See also
References
- ↑ Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 7. ISBN 978-1416002741.