Difference between revisions of "Serous borderline tumour"
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'''Serous borderline tumour''' is a Muellerian epithelial [[ovarian tumour]] with a behaviour that borders on [[malignant]]. | |||
It is also known as '''serous ovarian tumour of low malignant potential'''.<ref name=pmid10881733/> | |||
==General== | |||
*Usually benign. | |||
*Require long term follow-up. | |||
==Microscopic== | |||
Features:<ref name=Ref_GP399>{{Ref GP|399}}</ref> | |||
*Cuboidal to columnar epithelium with mild to moderate atypia. | |||
*No invasive. | |||
*"Sparse" mitoses. | |||
*+/-[[Psammoma bodies]]. | |||
*+/-Micropapillary architecture - often described as a ''medusa head'' pattern. | |||
DDx: | |||
*[[Serous carcinoma of the ovary]] - focus a with stromal invasion >5mm (linear measurement) ''or'' > 10 mm<sup>2</sup> (area).<ref name=Ref_GP399>{{Ref GP|399}}</ref> | |||
**Invasive cells are "pink", i.e. have abundant eosinophilic cytoplasm,<ref name=Ref_GP399/>; also, cells usu. large (~2-3x size of non-invasive component), and typically have an enlarged nucleus (~2x non-invasive component). | |||
*[[Clear cell carcinoma of the ovary]] - classically associated with [[endometriosis]], have simpler, smaller papillae without branching. | |||
Images: | |||
*[http://pubs.rsna.org/na101/home/literatum/publisher/rsna/journals/content/radiographics/2005/radiographics.2005.25.issue-6/rg.256055015/production/images/medium/g05nv16c4x.jpeg Serous ovarian LMP tumour (radiographics.rsna.org)].<ref name=pmid16284143>{{Cite journal | last1 = Burkholz | first1 = KJ. | last2 = Wood | first2 = BP. | last3 = Zuppan | first3 = C. | title = Best cases from the AFIP: Borderline papillary serous tumor of the right ovary. | journal = Radiographics | volume = 25 | issue = 6 | pages = 1689-92 | month = | year = | doi = 10.1148/rg.256055015 | PMID = 16284143 }}</ref> | |||
===Subclassification=== | |||
Typical subdivided into:<ref name=pmid21917305>{{Cite journal | last1 = Park | first1 = JY. | last2 = Kim | first2 = DY. | last3 = Kim | first3 = JH. | last4 = Kim | first4 = YM. | last5 = Kim | first5 = KR. | last6 = Kim | first6 = YT. | last7 = Nam | first7 = JH. | title = Micropapillary pattern in serous borderline ovarian tumors: does it matter? | journal = Gynecol Oncol | volume = 123 | issue = 3 | pages = 511-6 | month = Dec | year = 2011 | doi = 10.1016/j.ygyno.2011.08.008 | PMID = 21917305 }}</ref> | |||
*Micropapillary serous borderline tumour. | |||
*Typical serous borderline tumour (SBOT). | |||
==Sign out== | |||
<pre> | |||
Cyst and Right Fallopian Tube, Excision: | |||
- SEROUS BORDERLINE TUMOUR with micropapillary architecture, see comment. | |||
- Fallopian tube within normal limits. | |||
- NEGATIVE for evidence of invasion. | |||
Comment: | |||
The lesion appears to be confined to a cystic structure. | |||
</pre> | |||
==See also== | |||
*[[Ovarian tumours]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | |||
[[Category:Ovarian tumours]] | |||
Revision as of 02:07, 29 March 2016
Serous borderline tumour is a Muellerian epithelial ovarian tumour with a behaviour that borders on malignant.
It is also known as serous ovarian tumour of low malignant potential.[1]
General
- Usually benign.
- Require long term follow-up.
Microscopic
Features:[2]
- Cuboidal to columnar epithelium with mild to moderate atypia.
- No invasive.
- "Sparse" mitoses.
- +/-Psammoma bodies.
- +/-Micropapillary architecture - often described as a medusa head pattern.
DDx:
- Serous carcinoma of the ovary - focus a with stromal invasion >5mm (linear measurement) or > 10 mm2 (area).[2]
- Invasive cells are "pink", i.e. have abundant eosinophilic cytoplasm,[2]; also, cells usu. large (~2-3x size of non-invasive component), and typically have an enlarged nucleus (~2x non-invasive component).
- Clear cell carcinoma of the ovary - classically associated with endometriosis, have simpler, smaller papillae without branching.
Images:
Subclassification
Typical subdivided into:[4]
- Micropapillary serous borderline tumour.
- Typical serous borderline tumour (SBOT).
Sign out
Cyst and Right Fallopian Tube, Excision:
- SEROUS BORDERLINE TUMOUR with micropapillary architecture, see comment.
- Fallopian tube within normal limits.
- NEGATIVE for evidence of invasion.
Comment:
The lesion appears to be confined to a cystic structure.
See also
References
- ↑ Cite error: Invalid
<ref>tag; no text was provided for refs namedpmid10881733 - ↑ 2.0 2.1 2.2 Nucci, Marisa R.; Oliva, Esther (2009). Gynecologic Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 399. ISBN 978-0443069208.
- ↑ Burkholz, KJ.; Wood, BP.; Zuppan, C.. "Best cases from the AFIP: Borderline papillary serous tumor of the right ovary.". Radiographics 25 (6): 1689-92. doi:10.1148/rg.256055015. PMID 16284143.
- ↑ Park, JY.; Kim, DY.; Kim, JH.; Kim, YM.; Kim, KR.; Kim, YT.; Nam, JH. (Dec 2011). "Micropapillary pattern in serous borderline ovarian tumors: does it matter?". Gynecol Oncol 123 (3): 511-6. doi:10.1016/j.ygyno.2011.08.008. PMID 21917305.