Difference between revisions of "Rheumatoid lung nodule"
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'''Rheumatoid lung nodule''', also '''rheumatoid nodule of the lung''', is an uncommon benign lung lesion associated with [[rheumatoid arthritis]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = mixed inflammatory infiltrate, +/-[[giant cells]], no micro-organisms | |||
| Subtypes = | |||
| LMDDx = necrotic pulmonary nodules in [[Crohn's disease]], [[infectious pneumonia]], [[amyloidosis]] of lung | |||
| Stains = ZN -ve, GMS -ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lung]] - see ''[[medical lung diseases]]'' | |||
| Assdx = [[rheumatoid arthritis]] | |||
| Syndromes = | |||
| Clinicalhx = +/-hx of rheumatoid arthritis | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = upper lung fields, peripheral, round, +/-cavitation | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = only lung lesions - esp. malignancy | |||
| Tx = | |||
}} | |||
'''Rheumatoid lung nodule''', also '''rheumatoid nodule of the lung''' and '''pulmonary rheumatoid nodule''', is an uncommon benign lung lesion associated with [[rheumatoid arthritis]]. | |||
''Rheumatoid lung disease'' redirects here. ''[[Rheumatoid pleuritis]]'' is dealt with separately. | ''Rheumatoid lung disease'' redirects here. ''[[Rheumatoid pleuritis]]'' is dealt with separately. | ||
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*Mixed inflammatory infiltrate. | *Mixed inflammatory infiltrate. | ||
*+/-[[Giant cells]]. | *+/-[[Giant cells]]. | ||
*No micro-organisms. | |||
Dx: | Dx: | ||
*Necrotic pulmonary nodule in [[Crohn's disease]]. | *Necrotic pulmonary nodule in [[Crohn's disease]]. | ||
*[[Infectious pneumonia]]. | *[[Infectious pneumonia]]. | ||
*[[Amyloidosis]]<ref name=pmid17037396>{{cite journal |authors=Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H |title=Nodular pulmonary amyloidosis |journal=Jpn J Thorac Cardiovasc Surg |volume=54 |issue=9 |pages=399–401 |date=September 2006 |pmid=17037396 |doi=10.1007/s11748-006-0015-4 |url=}}</ref> - reported in the context with rheumatoid arthritis.<ref name=pmid17332981>{{cite journal |authors=Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH |title=Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis |journal=Clin Rheumatol |volume=26 |issue=10 |pages=1797–8 |date=October 2007 |pmid=17332981 |doi=10.1007/s10067-007-0552-y |url=}}</ref> | |||
===Images=== | ===Images=== | ||
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*[[ZN stain]] -ve for AFB. | *[[ZN stain]] -ve for AFB. | ||
*[[GMS stain]] -ve for [[fungal organisms]]. | *[[GMS stain]] -ve for [[fungal organisms]]. | ||
*[[Congo red]] -ve. | |||
==See also== | ==See also== | ||
Latest revision as of 16:36, 3 March 2022
| Rheumatoid lung nodule | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | mixed inflammatory infiltrate, +/-giant cells, no micro-organisms |
| LM DDx | necrotic pulmonary nodules in Crohn's disease, infectious pneumonia, amyloidosis of lung |
| Stains | ZN -ve, GMS -ve |
| Site | lung - see medical lung diseases |
|
| |
| Associated Dx | rheumatoid arthritis |
| Clinical history | +/-hx of rheumatoid arthritis |
| Prevalence | uncommon |
| Radiology | upper lung fields, peripheral, round, +/-cavitation |
| Clin. DDx | only lung lesions - esp. malignancy |
Rheumatoid lung nodule, also rheumatoid nodule of the lung and pulmonary rheumatoid nodule, is an uncommon benign lung lesion associated with rheumatoid arthritis.
Rheumatoid lung disease redirects here. Rheumatoid pleuritis is dealt with separately.
General
- Rare.[1]
Common associations:[1]
- Male.
- RF +ve.
- Skin nodules - see rheumatoid nodule.
Gross/radiology
Features:[1]
- Usually upper lung fields, peripheral and round.
- +/-Cavitation (~50% of cases).
Microscopic
Features:[2]
- Mixed inflammatory infiltrate.
- +/-Giant cells.
- No micro-organisms.
Dx:
- Necrotic pulmonary nodule in Crohn's disease.
- Infectious pneumonia.
- Amyloidosis[3] - reported in the context with rheumatoid arthritis.[4]
Images
www:
Stains
- ZN stain -ve for AFB.
- GMS stain -ve for fungal organisms.
- Congo red -ve.
See also
References
- ↑ 1.0 1.1 1.2 Gómez Herrero, H.; Arraiza Sarasa, M.; Rubio Marco, I.; García de Eulate Martín-Moro, I.. "Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases.". Reumatol Clin 8 (4): 212-5. doi:10.1016/j.reuma.2011.09.004. PMID 22265461.
- ↑ 2.0 2.1 2.2 Chhakchhuak, CL.; Khosravi, M.; Lohr, KM. (2013). "Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature.". Case Rep Rheumatol 2013: 621340. doi:10.1155/2013/621340. PMID 23984160.
- ↑ Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H (September 2006). "Nodular pulmonary amyloidosis". Jpn J Thorac Cardiovasc Surg 54 (9): 399–401. doi:10.1007/s11748-006-0015-4. PMID 17037396.
- ↑ Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH (October 2007). "Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis". Clin Rheumatol 26 (10): 1797–8. doi:10.1007/s10067-007-0552-y. PMID 17332981.