Difference between revisions of "Urothelial papilloma"

From Libre Pathology
Jump to navigation Jump to search
(split out)
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Urothelial papilloma - alt -- intermed mag.jpg
| Width      =
| Caption    = Urothelial papilloma. [[H&E stain]].
| Synonyms  =
| Micro      = papillary fronds with minimal branching or fusion, cytology and thickness of normal urothelium, no mitoses
| Subtypes  =
| LMDDx      = [[low grade papillary urothelial carcinoma]], [[PUNLMP]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[urothelium]] - typically [[urinary bladder]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = other papillary lesions
| Tx        =
}}
'''Urothelial papilloma''' is a rare benign lesion of the [[urothelium]].
'''Urothelial papilloma''' is a rare benign lesion of the [[urothelium]].


Line 8: Line 39:
*If the person has a history of a low grade papillary urothelial carcinoma... it is likely a low grade papillary urothelial carcinoma.
*If the person has a history of a low grade papillary urothelial carcinoma... it is likely a low grade papillary urothelial carcinoma.
*These cases are a consensus diagnosis, i.e. you show it to a colleague... if they agree you can call it.  
*These cases are a consensus diagnosis, i.e. you show it to a colleague... if they agree you can call it.  
==Gross==
*Exophytic lesion.


==Microscopic==
==Microscopic==
Line 21: Line 55:
*[[Low grade papillary urothelial carcinoma]].
*[[Low grade papillary urothelial carcinoma]].
*[[PUNLMP]].
*[[PUNLMP]].
===Images===
<gallery>
Image: Urothelial papilloma -- very low mag.jpg | UP - very low mag.
Image: Urothelial papilloma -- low mag.jpg | UP - low mag.
Image: Urothelial papilloma -- intermed mag.jpg | UP - intermed mag.
Image: Urothelial papilloma -- high mag.jpg | UP - high mag.
Image: Urothelial papilloma -- very high mag.jpg | UP - very high mag.
Image: Urothelial papilloma - alt 1 -- high mag.jpg | UP - high mag.
Image: Urothelial papilloma - alt 2 -- high mag.jpg | UP - high mag.
</gallery>
==Sign out==
<pre>
Urinary Bladder, Biopsy:
- Urothelial papilloma. 
</pre>
===Microscopic===
The sections show superficial fragments of a papillary urothelial lesion. The cytology and thickness is that of normal urothelium. No proliferation is apparent.


==See also==
==See also==
*[[Urothelium]].
*[[Urothelium]].
*[[PUNLMP]].
*[[PUNLMP]].
*[[Inverted urothelial papilloma]].


==References==
==References==

Latest revision as of 18:19, 19 September 2022

Urothelial papilloma
Diagnosis in short

Urothelial papilloma. H&E stain.

LM papillary fronds with minimal branching or fusion, cytology and thickness of normal urothelium, no mitoses
LM DDx low grade papillary urothelial carcinoma, PUNLMP
Site urothelium - typically urinary bladder

Prevalence uncommon
Prognosis benign
Clin. DDx other papillary lesions

Urothelial papilloma is a rare benign lesion of the urothelium.

General

  • Rare.[1]
  • Males > females (1.9:1).[1]

Notes:

  • If the person has a history of a low grade papillary urothelial carcinoma... it is likely a low grade papillary urothelial carcinoma.
  • These cases are a consensus diagnosis, i.e. you show it to a colleague... if they agree you can call it.

Gross

  • Exophytic lesion.

Microscopic

Features:[2]

  • Papillary fronds.
  • Minimal branching or fusion.
  • Cytological features of normal urothelium.
    • Normal urothelium approx. 2x the size of stromal lymphocytes.[3]
  • No mitoses.
  • Thickness < 7 cells.[citation needed]

DDx:

Images

Sign out

Urinary Bladder, Biopsy: 
	- Urothelial papilloma.  

Microscopic

The sections show superficial fragments of a papillary urothelial lesion. The cytology and thickness is that of normal urothelium. No proliferation is apparent.

See also

References

  1. 1.0 1.1 Al Bashir, S.; Yilmaz, A.; Gotto, G.; Trpkov, K. (Jan 2014). "Long term outcome of primary urothelial papilloma: a single institution cohort.". Pathology 46 (1): 37-40. doi:10.1097/PAT.0000000000000029. PMID 24300727.
  2. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 310. ISBN 978-0781765275.
  3. Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 161. ISBN 978-0443066771.