Difference between revisions of "Eccrine spiradenoma"
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'''Eccrine spiradenoma''' is a benign skin thingy. | '''Eccrine spiradenoma''', also '''spiradenoma''',<ref>URL: [http://emedicine.medscape.com/article/1062079-overview http://emedicine.medscape.com/article/1062079-overview]. Accessed on: 9 May 2011.</ref> is a benign skin thingy. There is case series of malignant ones.<ref name=pmid20851376>{{Cite journal | last1 = Andreoli | first1 = MT. | last2 = Itani | first2 = KM. | title = Malignant eccrine spiradenoma: a meta-analysis of reported cases. | journal = Am J Surg | volume = 201 | issue = 5 | pages = 688-92 | month = May | year = 2011 | doi = 10.1016/j.amjsurg.2010.04.015 | PMID = 20851376 }}</ref> | ||
==General== | ==General== | ||
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*Apocrine differentiation, i.e. apocrine snouts. | *Apocrine differentiation, i.e. apocrine snouts. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Eccrine_spiradenoma_-_very_low_mag.jpg Eccrine spiradenoma - very low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Eccrine_spiradenoma_-_very_high_mag.jpg Eccrine spiradenoma - very high mag. (WC)]. | |||
*[http://dermimages.med.jhmi.edu/images/spiradenoma_2_060109.jpg Eccrine spiradenoma (dermimages.med.jhmi.edu)].<ref name=dermatlas>URL: [http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448 http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448]. Accessed on: 29 November 2010.</ref> | |||
==IHC== | |||
Features:<ref name=pmid9129700>{{Cite journal | last1 = Meybehm | first1 = M. | last2 = Fischer | first2 = HP. | title = Spiradenoma and dermal cylindroma: comparative immunohistochemical analysis and histogenetic considerations. | journal = Am J Dermatopathol | volume = 19 | issue = 2 | pages = 154-61 | month = Apr | year = 1997 | doi = | PMID = 9129700 }}</ref> | |||
*S100 +ve. | |||
*Keratins 7, 8, and 18 +ve. | |||
Notes: | |||
*IHC profile essentially identical to dermal cylindroma.<ref name=pmid9129700/> | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Dermatopathology]] | [[Category:Dermatopathology]] | ||
Revision as of 03:47, 10 May 2011
Eccrine spiradenoma, also spiradenoma,[1] is a benign skin thingy. There is case series of malignant ones.[2]
General
- A painful skin lesion.
- Benign.
Microscopic
Features:[3]
- Dense nests of cells in the dermis; "dermal blue balls".
- Apocrine differentiation, i.e. apocrine snouts.
Images:
- Eccrine spiradenoma - very low mag. (WC).
- Eccrine spiradenoma - very high mag. (WC).
- Eccrine spiradenoma (dermimages.med.jhmi.edu).[3]
IHC
Features:[4]
- S100 +ve.
- Keratins 7, 8, and 18 +ve.
Notes:
- IHC profile essentially identical to dermal cylindroma.[4]
See also
References
- ↑ URL: http://emedicine.medscape.com/article/1062079-overview. Accessed on: 9 May 2011.
- ↑ Andreoli, MT.; Itani, KM. (May 2011). "Malignant eccrine spiradenoma: a meta-analysis of reported cases.". Am J Surg 201 (5): 688-92. doi:10.1016/j.amjsurg.2010.04.015. PMID 20851376.
- ↑ 3.0 3.1 URL: http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448. Accessed on: 29 November 2010.
- ↑ 4.0 4.1 Meybehm, M.; Fischer, HP. (Apr 1997). "Spiradenoma and dermal cylindroma: comparative immunohistochemical analysis and histogenetic considerations.". Am J Dermatopathol 19 (2): 154-61. PMID 9129700.