Difference between revisions of "Renal tumours with eosinophilic cytoplasm"

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[[Image:Oncocytic_chromophobe_rcc_high_mag.jpg|thumb|right|200px|A renal tumour with an eosinophilic cytoplasm. (WC/Nephron)]]
[[Image:Eosinophilic variant of chromophobe renal cell carcinoma -- very high mag.jpg|thumb|right|A renal tumour with an eosinophilic cytoplasm ([[chromophobe RCC]]). (WC/Nephron)]]  
'''[[Renal tumours]] with eosinophilic cytoplasm''' are relatively common and have a differential diagnosis.
'''[[Renal tumours]] with eosinophilic cytoplasm''', also '''eosinophilic renal tumours''' and '''kidney tumours with eosinophilic cytoplasm''', are relatively common and have a [[differential diagnosis]].


==Common==
==Common==
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==Less common==
==Less common==
*[[Clear cell renal cell carcinoma]], eosinophilic variant<ref name=pmid1780705>{{Cite journal  | last1 = Engel | first1 = U. | last2 = Horn | first2 = T. | title = Eosinophilic renal cell tumours. A study on tumour heterogeneity with special emphasis on oncocytes. | journal = Scand J Urol Nephrol | volume = 25 | issue = 4 | pages = 297-301 | month =  | year = 1991 | doi =  | PMID = 1780705 }}</ref> - often high-grade/aggressive tumours.
*[[Clear cell renal cell carcinoma]], eosinophilic variant<ref name=pmid1780705>{{Cite journal  | last1 = Engel | first1 = U. | last2 = Horn | first2 = T. | title = Eosinophilic renal cell tumours. A study on tumour heterogeneity with special emphasis on oncocytes. | journal = Scand J Urol Nephrol | volume = 25 | issue = 4 | pages = 297-301 | month =  | year = 1991 | doi =  | PMID = 1780705 }}</ref> - often high-grade/aggressive tumours.
*[[Papillary renal cell carcinoma]], eosinophilic variant.
*[[Papillary renal cell carcinoma]], oncocytic variant.<ref name=pmid23826421>{{Cite journal  | last1 = Xia | first1 = QY. | last2 = Rao | first2 = Q. | last3 = Shen | first3 = Q. | last4 = Shi | first4 = SS. | last5 = Li | first5 = L. | last6 = Liu | first6 = B. | last7 = Zhang | first7 = J. | last8 = Wang | first8 = YF. | last9 = Shi | first9 = QL. | title = Oncocytic papillary renal cell carcinoma: a clinicopathological study emphasizing distinct morphology, extended immunohistochemical profile and cytogenetic features. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 7 | pages = 1392-9 | month =  | year = 2013 | doi =  | PMID = 23826421 }}</ref>


==Rare stuff==
==Rare stuff==
[[Image:Eosinophilic, solid and cystic renal cell carcinoma - solid -- very high mag.jpg|thumb|right|[[ESC-RCC]], an evolving entity with eosinophilic cytoplasm. [[H&E stain]]. (WC)]]
[[Image:Low grade oncocytic renal tumour -- very high mag.jpg|thumb|right|Low-grade oncocytic renal tumour, an evolving entity with eosinophilic cytoplasm. [[H&E stain]].]]
*[[Angiomyolipoma]], epithelioid.
*[[Angiomyolipoma]], epithelioid.
*[[Xp11.2 translocation carcinoma]].
*[[Xp11.2 translocation carcinoma]].
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*[[Tubulocystic carcinoma]].<ref name=pmid25357116/>
*[[Tubulocystic carcinoma]].<ref name=pmid25357116/>
*[[Acquired cystic disease-associated renal cell carcinoma]].<ref name=pmid25357116/>
*[[Acquired cystic disease-associated renal cell carcinoma]].<ref name=pmid25357116/>
*Hybrid tumour.<ref name=pmid25357116/>
*[[Renal hybrid oncocytic/chromophobe tumour]].<ref name=pmid25357116/>
*[[Renal oncocytosis]].
*[[Unclassified renal cell carcinoma]].
*[[Juxtaglomerular cell tumour]].
*[[Succinate dehydrogenase-deficient renal cell carcinoma]].
*[[Eosinophilic solid and cystic renal cell carcinoma]].<ref name=pmid26414221>{{Cite journal  | last1 = Trpkov | first1 = K. | last2 = Hes | first2 = O. | last3 = Bonert | first3 = M. | last4 = Lopez | first4 = JI. | last5 = Bonsib | first5 = SM. | last6 = Nesi | first6 = G. | last7 = Comperat | first7 = E. | last8 = Sibony | first8 = M. | last9 = Berney | first9 = DM. | title = Eosinophilic, Solid, and Cystic Renal Cell Carcinoma: Clinicopathologic Study of 16 Unique, Sporadic Neoplasms Occurring in Women. | journal = Am J Surg Pathol | volume =  | issue =  | pages =  | month = Sep | year = 2015 | doi = 10.1097/PAS.0000000000000508 | PMID = 26414221 }}</ref>
*[[ALK translocation renal cell carcinoma]].<ref name=ref27554841 >{{Cite journal  | last1 = Jeanneau | first1 = M. | last2 = Gregoire | first2 = V. | last3 = Desplechain | first3 = C. | last4 = Escande | first4 = F. | last5 = Tica | first5 = DP. | last6 = Aubert | first6 = S. | last7 = Leroy | first7 = X. | title = ALK rearrangements-associated renal cell carcinoma (RCC) with unique pathological features in an adult. | journal = Pathol Res Pract | volume = 212 | issue = 11 | pages = 1064-1066 | month = Nov | year = 2016 | doi = 10.1016/j.prp.2016.07.015 | PMID = 27554841 }}</ref>


===Proposed entities===
===Proposed entities===
*Eosinophilic cystic and solid renal tumour.
*[[Follicular thyroid-like renal cell carcinoma]].<ref name=pmid25357116/>
*[[Follicular thyroid-like renal cell carcinoma]].<ref name=pmid25357116/>
*[[Eosinophilic vacuolated tumour]] - previously ''high-grade oncocytic renal tumour''.
*[[Papillary renal neoplasm with reverse polarity]] (PRNRP).<ref name=pmid31135486>{{cite journal |authors=Al-Obaidy KI, Eble JN, Cheng L, Williamson SR, Sakr WA, Gupta N, Idrees MT, Grignon DJ |title=Papillary Renal Neoplasm With Reverse Polarity: A Morphologic, Immunohistochemical, and Molecular Study |journal=Am J Surg Pathol |volume=43 |issue=8 |pages=1099–1111 |date=August 2019 |pmid=31135486 |doi=10.1097/PAS.0000000000001288 |url=}}</ref>
*[[Low-grade oncocytic renal tumour]] (renal oncocytic tumour that is CD117 negative and CK7 positive).
==See also==
*[[Clear cells in the kidney]].


==References==
==References==

Latest revision as of 16:28, 22 January 2024

A renal tumour with an eosinophilic cytoplasm (chromophobe RCC). (WC/Nephron)

Renal tumours with eosinophilic cytoplasm, also eosinophilic renal tumours and kidney tumours with eosinophilic cytoplasm, are relatively common and have a differential diagnosis.

Common

Less common

Rare stuff

ESC-RCC, an evolving entity with eosinophilic cytoplasm. H&E stain. (WC)
Low-grade oncocytic renal tumour, an evolving entity with eosinophilic cytoplasm. H&E stain.

Proposed entities

See also

References

  1. ↑ Engel, U.; Horn, T. (1991). "Eosinophilic renal cell tumours. A study on tumour heterogeneity with special emphasis on oncocytes.". Scand J Urol Nephrol 25 (4): 297-301. PMID 1780705.
  2. ↑ Xia, QY.; Rao, Q.; Shen, Q.; Shi, SS.; Li, L.; Liu, B.; Zhang, J.; Wang, YF. et al. (2013). "Oncocytic papillary renal cell carcinoma: a clinicopathological study emphasizing distinct morphology, extended immunohistochemical profile and cytogenetic features.". Int J Clin Exp Pathol 6 (7): 1392-9. PMID 23826421.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Kryvenko, ON.; Jorda, M.; Argani, P.; Epstein, JI. (Nov 2014). "Diagnostic approach to eosinophilic renal neoplasms.". Arch Pathol Lab Med 138 (11): 1531-41. doi:10.5858/arpa.2013-0653-RA. PMID 25357116.
  4. ↑ Trpkov, K.; Hes, O.; Bonert, M.; Lopez, JI.; Bonsib, SM.; Nesi, G.; Comperat, E.; Sibony, M. et al. (Sep 2015). "Eosinophilic, Solid, and Cystic Renal Cell Carcinoma: Clinicopathologic Study of 16 Unique, Sporadic Neoplasms Occurring in Women.". Am J Surg Pathol. doi:10.1097/PAS.0000000000000508. PMID 26414221.
  5. ↑ Jeanneau, M.; Gregoire, V.; Desplechain, C.; Escande, F.; Tica, DP.; Aubert, S.; Leroy, X. (Nov 2016). "ALK rearrangements-associated renal cell carcinoma (RCC) with unique pathological features in an adult.". Pathol Res Pract 212 (11): 1064-1066. doi:10.1016/j.prp.2016.07.015. PMID 27554841.
  6. ↑ Al-Obaidy KI, Eble JN, Cheng L, Williamson SR, Sakr WA, Gupta N, Idrees MT, Grignon DJ (August 2019). "Papillary Renal Neoplasm With Reverse Polarity: A Morphologic, Immunohistochemical, and Molecular Study". Am J Surg Pathol 43 (8): 1099–1111. doi:10.1097/PAS.0000000000001288. PMID 31135486.

External links

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