Difference between revisions of "Eyelid"

From Libre Pathology
Jump to navigation Jump to search
(+image)
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image: Closed human eye, superior view.jpg|thumb|right|A photograph showing the superior eyelid. (WC/Rapidreflex)]]
[[Image:Syringoma -- low mag.jpg|thumb|right|A [[micrograph]] showing a [[syringoma]]. These are typically lower eyelid tumours. [[H&E stain]].]]
The '''eyelid''' is occasionally sent to [[pathology]].  Information about the eye is found in the ''[[eye]]'' article.
The '''eyelid''' is occasionally sent to [[pathology]].  Information about the eye is found in the ''[[eye]]'' article.


Line 7: Line 9:
***One was [[squamous carcinoma]].
***One was [[squamous carcinoma]].


Malignant tumours:<ref name=pmid9488271>{{cite journal |authors=Margo CE, Mulla ZD |title=Malignant tumors of the eyelid: a population-based study of non-basal cell and non-squamous cell malignant neoplasms |journal=Arch Ophthalmol |volume=116 |issue=2 |pages=195–8 |date=February 1998 |pmid=9488271 |doi=10.1001/archopht.116.2.195 |url=}}</ref>
===Common lesions===
The most common lesion - as per a large series of 1,541 cases:<ref name=pmid26028084/>
*[[Squamous papilloma]].
*[[Nevus]].
*[[Seborrheic keratosis]].
*Hydrocystomas.
*[[Xanthelasma]].
*[[Epidermal cyst]].
 
==Malignant tumours of the eyelid==
Malignant eyelid tumour in order of frequency:<ref name=pmid9488271>{{cite journal |authors=Margo CE, Mulla ZD |title=Malignant tumors of the eyelid: a population-based study of non-basal cell and non-squamous cell malignant neoplasms |journal=Arch Ophthalmol |volume=116 |issue=2 |pages=195–8 |date=February 1998 |pmid=9488271 |doi=10.1001/archopht.116.2.195 |url=}}</ref>
*[[Basal cell carcinoma]].
*[[Basal cell carcinoma]].
*[[Squamous cell carcinoma]].
*[[Squamous cell carcinoma]].
Line 16: Line 28:
*Mucinous adenocarcinoma.
*Mucinous adenocarcinoma.
*Adenocarcinoma not otherwise specified.
*Adenocarcinoma not otherwise specified.
*Adexal carcinoma not otherwise specified.
*Adnexal carcinoma not otherwise specified.
*Sweat gland carcinoma.
*Sweat gland carcinoma.


Line 26: Line 38:
*~8% of eyelid tumours in one series.<ref name=pmid26028084/>
*~8% of eyelid tumours in one series.<ref name=pmid26028084/>
*Type of [[xanthoma]].<ref name=pmid25949023>{{Cite journal  | last1 = Pathania | first1 = V. | last2 = Chatterjee | first2 = M. | title = Ultrapulse carbon dioxide laser ablation of xanthelasma palpebrarum: a case series. | journal = J Cutan Aesthet Surg | volume = 8 | issue = 1 | pages = 46-9 | month =  | year =  | doi = 10.4103/0974-2077.155084 | PMID = 25949023 }}</ref>
*Type of [[xanthoma]].<ref name=pmid25949023>{{Cite journal  | last1 = Pathania | first1 = V. | last2 = Chatterjee | first2 = M. | title = Ultrapulse carbon dioxide laser ablation of xanthelasma palpebrarum: a case series. | journal = J Cutan Aesthet Surg | volume = 8 | issue = 1 | pages = 46-9 | month =  | year =  | doi = 10.4103/0974-2077.155084 | PMID = 25949023 }}</ref>
**It is said that a ''xanthoma'' can be anywhere. If it is on the eyelid it is a ''xanthelasma''; a ''xanthelasma'' is a xanthoma of the eyelid.<ref>URL: [https://www.merriam-webster.com/medical/xanthelasma https://www.merriam-webster.com/medical/xanthelasma]. Accessed on: May 1, 2023.</ref>
*Associated with increased serum lipid levels.<ref name=pmid23503059>{{Cite journal  | last1 = Rubinstein | first1 = TJ. | last2 = Mehta | first2 = MP. | last3 = Schoenfield | first3 = L. | last4 = Perry | first4 = JD. | title = Orbital xanthogranuloma in an adult patient with xanthelasma palpebrarum and hypercholesterolemia. | journal = Ophthal Plast Reconstr Surg | volume = 30 | issue = 1 | pages = e6-8 | month =  | year =  | doi = 10.1097/IOP.0b013e3182873d13 | PMID = 23503059 }}</ref>
*Associated with increased serum lipid levels.<ref name=pmid23503059>{{Cite journal  | last1 = Rubinstein | first1 = TJ. | last2 = Mehta | first2 = MP. | last3 = Schoenfield | first3 = L. | last4 = Perry | first4 = JD. | title = Orbital xanthogranuloma in an adult patient with xanthelasma palpebrarum and hypercholesterolemia. | journal = Ophthal Plast Reconstr Surg | volume = 30 | issue = 1 | pages = e6-8 | month =  | year =  | doi = 10.1097/IOP.0b013e3182873d13 | PMID = 23503059 }}</ref>
**Incidence of elevated cholesterol is higher in younger patients.<ref name=Ref_Derm628>{{Ref Derm|628}}</ref>
**Incidence of elevated cholesterol is higher in younger patients.<ref name=Ref_Derm628>{{Ref Derm|628}}</ref>
Line 47: Line 60:
- Benign skin tag with rare foamy histiocytes in keeping with an early xanthelasma.
- Benign skin tag with rare foamy histiocytes in keeping with an early xanthelasma.
- NEGATIVE for malignancy.
- NEGATIVE for malignancy.
Comment:
Xanthelasma may be associated with metabolic abnormalities. A lipid profile is suggested if not done recently. 
</pre>
</pre>


==Chalazion==
==Chalazion==
{{Main|Chalazion}}
{{Main|Chalazion}}
==Syringoma==
{{Main|Syringoma}}


==See also==
==See also==

Latest revision as of 03:43, 1 November 2024

A photograph showing the superior eyelid. (WC/Rapidreflex)
A micrograph showing a syringoma. These are typically lower eyelid tumours. H&E stain.

The eyelid is occasionally sent to pathology. Information about the eye is found in the eye article.

General

Common lesions

The most common lesion - as per a large series of 1,541 cases:[1]

Malignant tumours of the eyelid

Malignant eyelid tumour in order of frequency:[2]

Specific entities

Xanthelasma

  • Xanthelasma palpebrarum redirects here.

General

  • ~8% of eyelid tumours in one series.[1]
  • Type of xanthoma.[3]
    • It is said that a xanthoma can be anywhere. If it is on the eyelid it is a xanthelasma; a xanthelasma is a xanthoma of the eyelid.[4]
  • Associated with increased serum lipid levels.[5]
    • Incidence of elevated cholesterol is higher in younger patients.[6]

Gross

  • Exophytic lesion (on eyelid or around it) - classically yellow.

DDx:

Microscopic

Features:

  • Collection of foamy histiocytes within the dermis.

DDx:

Sign out

Eyelid, Lesion Right Upper Lid, Excision:
- Benign skin tag with rare foamy histiocytes in keeping with an early xanthelasma.
- NEGATIVE for malignancy.

Comment:
Xanthelasma may be associated with metabolic abnormalities. A lipid profile is suggested if not done recently.

Chalazion

Main article: Chalazion

Syringoma

Main article: Syringoma

See also

References

  1. ↑ 1.0 1.1 1.2 Gundogan, FC.; Yolcu, U.; Tas, A.; Sahin, OF.; Uzun, S.; Cermik, H.; Ozaydin, S.; Ilhan, A. et al. (2015). "Eyelid tumors: clinical data from an eye center in Ankara, Turkey.". Asian Pac J Cancer Prev 16 (10): 4265-9. PMID 26028084.
  2. ↑ Margo CE, Mulla ZD (February 1998). "Malignant tumors of the eyelid: a population-based study of non-basal cell and non-squamous cell malignant neoplasms". Arch Ophthalmol 116 (2): 195–8. doi:10.1001/archopht.116.2.195. PMID 9488271.
  3. ↑ Pathania, V.; Chatterjee, M.. "Ultrapulse carbon dioxide laser ablation of xanthelasma palpebrarum: a case series.". J Cutan Aesthet Surg 8 (1): 46-9. doi:10.4103/0974-2077.155084. PMID 25949023.
  4. ↑ URL: https://www.merriam-webster.com/medical/xanthelasma. Accessed on: May 1, 2023.
  5. ↑ Rubinstein, TJ.; Mehta, MP.; Schoenfield, L.; Perry, JD.. "Orbital xanthogranuloma in an adult patient with xanthelasma palpebrarum and hypercholesterolemia.". Ophthal Plast Reconstr Surg 30 (1): e6-8. doi:10.1097/IOP.0b013e3182873d13. PMID 23503059.
  6. ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 628. ISBN 978-0443066542.
Retrieved from "https://librepathology.org/w/index.php?title=Eyelid&oldid=53296"