Difference between revisions of "Mast cell"

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The '''mast cell''' is an uncommonly cell that occasionally causes problems.
The '''mast cell''' is an uncommonly cell that occasionally causes problems.


==Morphology==
==Microscopic==
Features:
Features:
*Lymphocyte-like with more cytoplasm that is granular.
*Ovoid/round cell with moderate amount of gray granular cytoplasm.
**Cells may have spindled or stellate morphology.
*Nuclear ovoid/round.
**Tend to be more abundant around vessels.
**No obvious nucleolus.
*May be more abundant around [[blood vessels]].


Notes:
Notes:
*Lymphocyte vs. mast cell:
*Lymphocyte vs. mast cell:
**Lymphocytes = round; mast cells = ovoid.  
**Lymphocytes = round; mast cells = ovoid.  
Image:
*[http://www.jameswpattersonmd.com/images/pages/urt_pigment4.jpg Mastocytosis (jameswpattersonmd.com)].<ref>URL: [http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434 http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434]. Accessed on: 7 September 2011.</ref>


==Diseases==
==Diseases==

Revision as of 20:24, 7 September 2011

The mast cell is an uncommonly cell that occasionally causes problems.

Microscopic

Features:

  • Ovoid/round cell with moderate amount of gray granular cytoplasm.
  • Nuclear ovoid/round.
    • No obvious nucleolus.
  • May be more abundant around blood vessels.

Notes:

  • Lymphocyte vs. mast cell:
    • Lymphocytes = round; mast cells = ovoid.

Image:

Diseases

Stains

IHC

  • CD117 +ve.

References

  1. URL: http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434. Accessed on: 7 September 2011.
  2. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 370-2. ISBN 978-1416054542.