Difference between revisions of "Angiolymphoid hyperplasia with eosinophilia"

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'''Angiolymphoid hyperplasia with eosinophilia''', abbreviated '''ALHE''', is a rare [[skin]] [[dermatopathology|pathology]].
'''Angiolymphoid hyperplasia with eosinophilia''', abbreviated '''ALHE''', is a rare [[skin]] [[dermatopathology|pathology]]. It is also known as ''epithelioid [[hemangioma]]''.<ref name=Ref_Derm548>{{Ref Derm|548}}</ref>


==General==
==General==
*Similar to ''[[Kimura disease]]''.<ref name=pmid21382284>{{Cite journal  | last1 = Zaraa | first1 = I. | last2 = Mlika | first2 = M. | last3 = Chouk | first3 = S. | last4 = Chelly | first4 = I. | last5 = Mokni | first5 = M. | last6 = Zitouna | first6 = M. | last7 = Osman | first7 = AB. | title = Angiolymphoid hyperplasia with eosinophilia: a study of 7 cases. | journal = Dermatol Online J | volume = 17 | issue = 2 | pages = 1 | month =  | year = 2011 | doi =  | PMID = 21382284 }}</ref>
*Similar to ''[[Kimura disease]]''.<ref name=pmid21382284>{{Cite journal  | last1 = Zaraa | first1 = I. | last2 = Mlika | first2 = M. | last3 = Chouk | first3 = S. | last4 = Chelly | first4 = I. | last5 = Mokni | first5 = M. | last6 = Zitouna | first6 = M. | last7 = Osman | first7 = AB. | title = Angiolymphoid hyperplasia with eosinophilia: a study of 7 cases. | journal = Dermatol Online J | volume = 17 | issue = 2 | pages = 1 | month =  | year = 2011 | doi =  | PMID = 21382284 | URL =http://dermatology.cdlib.org/1702/1_case_reports/1_10-00279/zaraa.html }}</ref>
*Very rare.
*Very rare.
*Typical patient: Caucasian, woman.<ref name=pmid21382284/>
*Typical patient: Caucasian, woman.<ref name=pmid21382284/>
*Hypothesized to be a precursor to lymphoma.<ref name=pmid18510751>{{Cite journal  | last1 = Gonzalez-Cuyar | first1 = LF. | last2 = Tavora | first2 = F. | last3 = Zhao | first3 = XF. | last4 = Wang | first4 = G. | last5 = Auerbach | first5 = A. | last6 = Aguilera | first6 = N. | last7 = Burke | first7 = AP. | title = Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process. | journal = Diagn Pathol | volume = 3 | issue =  | pages = 22 | month =  | year = 2008 | doi = 10.1186/1746-1596-3-22 | PMID = 18510751 }}</ref>


Clinical:
==Gross==
*Location: usually head and neck.<ref name=pmid18510751/>
*Skin papules ''or'' nodules.<ref name=pmid8733384>{{Cite journal  | last1 = Bartralot | first1 = R. | last2 = Garcia-Patos | first2 = V. | last3 = Hueto | first3 = J. | last4 = Huguet | first4 = P. | last5 = Raspall | first5 = G. | last6 = Castells | first6 = A. | title = Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature. | journal = Br J Dermatol | volume = 134 | issue = 4 | pages = 744-8 | month = Apr | year = 1996 | doi =  | PMID = 8733384 }}</ref>
*Skin papules ''or'' nodules.<ref name=pmid8733384>{{Cite journal  | last1 = Bartralot | first1 = R. | last2 = Garcia-Patos | first2 = V. | last3 = Hueto | first3 = J. | last4 = Huguet | first4 = P. | last5 = Raspall | first5 = G. | last6 = Castells | first6 = A. | title = Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature. | journal = Br J Dermatol | volume = 134 | issue = 4 | pages = 744-8 | month = Apr | year = 1996 | doi =  | PMID = 8733384 }}</ref>
*Location: usu. head and neck.
 
Image:
*[http://www.atlasdermatologico.com.br/ListaImagens/Angiolymphoid_Hyperplasia_With_Eosinophilia4.JPG ALHE (atlasdermatologico.com.br)].


==Microscopic==
==Microscopic==
Line 23: Line 27:
*[[Angiosarcoma]].
*[[Angiosarcoma]].
*[[Kaposi sarcoma]].
*[[Kaposi sarcoma]].
*[[Lymphoma]].
Image:
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802175600790 ALHE (surgicalpathologyatlas.com)].


==See also==
==See also==
Line 30: Line 38:
{{Reflist|2}}
{{Reflist|2}}


[[Category:Lymph node pathology]]
[[Category:Dermatopathology]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Latest revision as of 16:33, 4 June 2013

Angiolymphoid hyperplasia with eosinophilia, abbreviated ALHE, is a rare skin pathology. It is also known as epithelioid hemangioma.[1]

General

  • Similar to Kimura disease.[2]
  • Very rare.
  • Typical patient: Caucasian, woman.[2]
  • Hypothesized to be a precursor to lymphoma.[3]

Gross

  • Location: usually head and neck.[3]
  • Skin papules or nodules.[4]

Image:

Microscopic

Features:[2]

  • Marked vascular proliferation.
  • Few lymphoid follicles.
  • Moderate eosinophils.

Negative:

  • No fibrosis.

DDx:

Image:

See also

References

  1. ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 548. ISBN 978-0443066542.
  2. ↑ 2.0 2.1 2.2 Zaraa, I.; Mlika, M.; Chouk, S.; Chelly, I.; Mokni, M.; Zitouna, M.; Osman, AB. (2011). "Angiolymphoid hyperplasia with eosinophilia: a study of 7 cases.". Dermatol Online J 17 (2): 1. PMID 21382284.
  3. ↑ 3.0 3.1 Gonzalez-Cuyar, LF.; Tavora, F.; Zhao, XF.; Wang, G.; Auerbach, A.; Aguilera, N.; Burke, AP. (2008). "Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process.". Diagn Pathol 3: 22. doi:10.1186/1746-1596-3-22. PMID 18510751.
  4. ↑ Bartralot, R.; Garcia-Patos, V.; Hueto, J.; Huguet, P.; Raspall, G.; Castells, A. (Apr 1996). "Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature.". Br J Dermatol 134 (4): 744-8. PMID 8733384.
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