Difference between revisions of "Nevus lipomatosus superficialis"

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#redirect [[Non-malignant_skin_disease#Nevus_lipomatosus_superficialis]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      =
| Width      =
| Caption    =
| Synonyms  =
| Micro      = benign adipose tissue in the dermis - adipocytes in [[reticular dermis]] +/- [[papillary dermis]]
| Subtypes  =
| LMDDx      = [[lipoma]], [[fibroepithelial polyp]] (skin tag), [[intradermal nevus]] with adipocytes
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = soft, pedunculated lesion
| Grossing  =
| Site      = [[skin]] - usually lower trunk or gluteal region
| Assdx      =
| Syndromes  =
| Clinicalhx = usu. young adults
| Signs      =
| Symptoms  =
| Prevalence = rare
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Nevus lipomatosus superficialis''', abbreviated '''NLS''', is an uncommon benign skin lesion seen on young adults.
 
It is also known as '''nevus lipomatosus cutaneous superficialis''' (abbreviated '''NLCS''') and '''nevus lipomatosus'''.<ref name=pmid15677959>{{Cite journal  | last1 = Kaw | first1 = P. | last2 = Carlson | first2 = A. | last3 = Meyer | first3 = DR. | title = Nevus lipomatosus (pedunculated lipofibroma) of the eyelid. | journal = Ophthal Plast Reconstr Surg | volume = 21 | issue = 1 | pages = 74-6 | month = Jan | year = 2005 | doi =  | PMID = 15677959 }}</ref>
 
==General==
*Rare.
*Congenital - considered a [[hamartoma]].<ref name=pmid22984661/>
*Usually young adults.<ref>URL: [http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus]. Accessed on: 8 January 2013.</ref>
 
Clinically separated into:<ref name=pmid17288284>{{Cite journal  | last1 = Triki | first1 = S. | last2 = Mekni | first2 = A. | last3 = Haouet | first3 = S. | last4 = Mokni | first4 = M. | last5 = Kchir | first5 = N. | last6 = Ben Osman Dhahri | first6 = A. | last7 = Zitouna | first7 = M. | title = [Nevus lipomatosus cutaneous superficialis: a clinico-pathological study of 13 cases]. | journal = Tunis Med | volume = 84 | issue = 12 | pages = 800-2 | month = Dec | year = 2006 | doi =  | PMID = 17288284 }}</ref>
*''Solitary'' - one lesion.
*''Multiple'' - more than one lesion.
 
==Gross==
Features:<ref name=pmid22984661>{{Cite journal  | last1 = Goucha | first1 = S. | last2 = Khaled | first2 = A. | last3 = Zéglaoui | first3 = F. | last4 = Rammeh | first4 = S. | last5 = Zermani | first5 = R. | last6 = Fazaa | first6 = B. | title = Nevus lipomatosus cutaneous superficialis: Report of eight cases. | journal = Dermatol Ther (Heidelb) | volume = 1 | issue = 2 | pages = 25-30 | month = Dec | year = 2011 | doi = 10.1007/s13555-011-0006-y | PMID = 22984661  | PMC = 3437641 }}</ref>
*Pedunculated lesion.
*Soft.
*Usually lower trunk or gluteal region.<ref name=pmid1235780>{{Cite journal  | last1 = Jones | first1 = EW. | last2 = Marks | first2 = R. | last3 = Pongsehirun | first3 = D. | title = Naevus superficialis lipomatosus. A clinicopathological report of twenty cases. | journal = Br J Dermatol | volume = 93 | issue = 2 | pages = 121-33 | month = Aug | year = 1975 | doi =  | PMID = 1235780 }}</ref>
 
Image:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437641/figure/Fig1/ NLS (nih.gov)].<ref name=pmid22984661/>
 
==Microscopic==
Features:<ref name=pmid19495497>{{Cite journal  | last1 = Yap | first1 = FB. | title = Nevus lipomatosus superficialis. | journal = Singapore Med J | volume = 50 | issue = 5 | pages = e161-2 | month = May | year = 2009 | doi =  | PMID = 19495497 | URL = http://smj.sma.org.sg/5005/5005cr3.pdf }}</ref>
*Benign adipose tissue in the dermis.
**Adipocytes in [[reticular dermis]] +/- [[papillary dermis]].<ref name=pmid20673540>{{Cite journal  | last1 = Ghosh | first1 = SK. | last2 = Bandyopadhyay | first2 = D. | last3 = Jamadar | first3 = NS. | title = Nevus lipomatosus cutaneous superficialis: An unusual presentation. | journal = Dermatol Online J | volume = 16 | issue = 7 | pages = 12 | month =  | year = 2010 | doi =  | PMID = 20673540 }}</ref>
 
DDx:
*[[Lipoma]].
*[[Fibroepithelial polyp]] (skin tag).
*[[Intradermal nevus]] with adipocytes.<ref name=pmid9810886>{{Cite journal  | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi =  | PMID = 9810886 }}</ref>
 
===Images===
*[http://www.dermaamin.com/site/images/histo-pic/n/nevus-lipomatosus-superficialis/nevus-lipomatosus-superficialis1.jpg NLS (dermamin.com)].<ref>URL: [http://www.dermaamin.com/site/histopathology-of-the-skin/66-n/1971-nevus-lipomatosus-superficialis----.html http://www.dermaamin.com/site/histopathology-of-the-skin/66-n/1971-nevus-lipomatosus-superficialis----.html]. Accessed on: 7 March 2012.</ref>
*[http://www.humpath.com/IMG/jpg/nevus_superficialis_lipomatosus_01_1.jpg NLS (humpath.com)].<ref>URL: [http://www.humpath.com/spip.php?article8134 http://www.humpath.com/spip.php?article8134]. Accessed on: 17 December 2012.</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437641/figure/Fig3/ NLS (nih.gov)].<ref name=pmid22984661/>
*[http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus Nevus lipomatosus (dermpedia.org)].
 
==Sign out==
<pre>
Skin Lesion, Back - Right, Excision:
- Nevus lipomatosus superficialis.
- NEGATIVE for malignancy.
</pre>
 
===Block letters===
<pre>
SKIN LESION ("SKIN TAG"), LEFT HIP, EXCISION:
- NEVUS LIPOMATOSUS SUPERFICIALIS.
</pre>
 
==See also==
*[[Non-malignant skin disease]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Dermatopathology]]

Latest revision as of 22:17, 17 September 2015

Nevus lipomatosus superficialis
Diagnosis in short
LM benign adipose tissue in the dermis - adipocytes in reticular dermis +/- papillary dermis
LM DDx lipoma, fibroepithelial polyp (skin tag), intradermal nevus with adipocytes
Gross soft, pedunculated lesion
Site skin - usually lower trunk or gluteal region
Clinical history usu. young adults
Prevalence rare
Prognosis benign

Nevus lipomatosus superficialis, abbreviated NLS, is an uncommon benign skin lesion seen on young adults.

It is also known as nevus lipomatosus cutaneous superficialis (abbreviated NLCS) and nevus lipomatosus.[1]

General

Clinically separated into:[4]

  • Solitary - one lesion.
  • Multiple - more than one lesion.

Gross

Features:[2]

  • Pedunculated lesion.
  • Soft.
  • Usually lower trunk or gluteal region.[5]

Image:

Microscopic

Features:[6]

DDx:

Images

Sign out

Skin Lesion, Back - Right, Excision:
- Nevus lipomatosus superficialis.
- NEGATIVE for malignancy.

Block letters

SKIN LESION ("SKIN TAG"), LEFT HIP, EXCISION:
- NEVUS LIPOMATOSUS SUPERFICIALIS.

See also

References

  1. ↑ Kaw, P.; Carlson, A.; Meyer, DR. (Jan 2005). "Nevus lipomatosus (pedunculated lipofibroma) of the eyelid.". Ophthal Plast Reconstr Surg 21 (1): 74-6. PMID 15677959.
  2. ↑ 2.0 2.1 2.2 2.3 Goucha, S.; Khaled, A.; Zéglaoui, F.; Rammeh, S.; Zermani, R.; Fazaa, B. (Dec 2011). "Nevus lipomatosus cutaneous superficialis: Report of eight cases.". Dermatol Ther (Heidelb) 1 (2): 25-30. doi:10.1007/s13555-011-0006-y. PMC 3437641. PMID 22984661. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437641/.
  3. ↑ URL: http://www.dermpedia.org/dermpedia-textbook/nevus-lipomatosus. Accessed on: 8 January 2013.
  4. ↑ Triki, S.; Mekni, A.; Haouet, S.; Mokni, M.; Kchir, N.; Ben Osman Dhahri, A.; Zitouna, M. (Dec 2006). "[Nevus lipomatosus cutaneous superficialis: a clinico-pathological study of 13 cases].". Tunis Med 84 (12): 800-2. PMID 17288284.
  5. ↑ Jones, EW.; Marks, R.; Pongsehirun, D. (Aug 1975). "Naevus superficialis lipomatosus. A clinicopathological report of twenty cases.". Br J Dermatol 93 (2): 121-33. PMID 1235780.
  6. ↑ Yap, FB. (May 2009). "Nevus lipomatosus superficialis.". Singapore Med J 50 (5): e161-2. PMID 19495497.
  7. ↑ Ghosh, SK.; Bandyopadhyay, D.; Jamadar, NS. (2010). "Nevus lipomatosus cutaneous superficialis: An unusual presentation.". Dermatol Online J 16 (7): 12. PMID 20673540.
  8. ↑ Eng, W.; Cohen, PR. (Nov 1998). "Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells.". J Am Acad Dermatol 39 (5 Pt 1): 704-11. PMID 9810886.
  9. ↑ URL: http://www.dermaamin.com/site/histopathology-of-the-skin/66-n/1971-nevus-lipomatosus-superficialis----.html. Accessed on: 7 March 2012.
  10. ↑ URL: http://www.humpath.com/spip.php?article8134. Accessed on: 17 December 2012.
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