Difference between revisions of "Female adnexal tumour of probable Wolffian origin"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Female adnexal tumour of probable Wolffian origin - very high mag.jpg | |||
| Width = | |||
| Caption = FATWO. [[H&E stain]]. | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = | |||
| Stains = | |||
| IHC = vimentin +ve, AE1/AE3 +ve, CAM5.2 +ve, AR +ve (~80% of cases) | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = adnexa ([[ovary]]) | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = usu. benign | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Female adnexal tumour of probable Wolffian origin''', abbreviated '''FATWO''', is a rare usually benign tumour. | '''Female adnexal tumour of probable Wolffian origin''', abbreviated '''FATWO''', is a rare usually benign tumour. | ||
It is also known as '''Wolffian adnexal tumour'''. | It is also known as '''Wolffian adnexal tumour''', abbreviated '''WAT'''. | ||
==General== | ==General== | ||
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**May be malignant.<ref name=pmid21542539>{{Cite journal | last1 = Heller | first1 = DS. | last2 = Kadire | first2 = B. | last3 = Cracchiolo | first3 = B. | title = Malignant female adnexal tumor of probable Wolffian origin: a case report. | journal = J Reprod Med | volume = 56 | issue = 3-4 | pages = 175-7 | month = | year = | doi = | PMID = 21542539 }}</ref> | **May be malignant.<ref name=pmid21542539>{{Cite journal | last1 = Heller | first1 = DS. | last2 = Kadire | first2 = B. | last3 = Cracchiolo | first3 = B. | title = Malignant female adnexal tumor of probable Wolffian origin: a case report. | journal = J Reprod Med | volume = 56 | issue = 3-4 | pages = 175-7 | month = | year = | doi = | PMID = 21542539 }}</ref> | ||
==Gross= | ==Gross== | ||
Adnexal location - as the name suggests:<ref name=pmid10414506/> | Adnexal location - as the name suggests:<ref name=pmid10414506/> | ||
*Broad ligament of ovary. | *Broad ligament of ovary. |
Latest revision as of 03:23, 23 April 2015
Female adnexal tumour of probable Wolffian origin | |
---|---|
Diagnosis in short | |
FATWO. H&E stain. | |
IHC | vimentin +ve, AE1/AE3 +ve, CAM5.2 +ve, AR +ve (~80% of cases) |
Site | adnexa (ovary) |
| |
Prevalence | very rare |
Prognosis | usu. benign |
Female adnexal tumour of probable Wolffian origin, abbreviated FATWO, is a rare usually benign tumour.
It is also known as Wolffian adnexal tumour, abbreviated WAT.
General
Gross
Adnexal location - as the name suggests:[3]
- Broad ligament of ovary.
- Mesosalpinx.
- Ovarian hilus - less common.
Microscopic
Features:[3]
- Variable architecture:
- Tubular or glandular.
- Solid - spindle cells.
- Multicystic.
DDx:
Images
IHC
Features:[3]
- Vimentin +ve.
- AE1/AE3 +ve.
- CAM5.2 +ve.
- CK7 +ve -- focal, sometimes -ve.
- AR +ve ~80% of cases.
- Inhibin +ve ~70% of cases.
Others:[3]
- CK20 -ve.
- mCEA -ve.
See also
References
- ↑ Tianmin, X.; Weiqim, C.; Mianhua, C.; Xiaocui, L.; Hongwen, G.; Min, Y. (2012). "Tumor of the mesosalpinx: case report of a female adnexal tumor of probable Wolffian origin.". Eur J Gynaecol Oncol 33 (2): 233-5. PMID 22611973.
- ↑ Heller, DS.; Kadire, B.; Cracchiolo, B.. "Malignant female adnexal tumor of probable Wolffian origin: a case report.". J Reprod Med 56 (3-4): 175-7. PMID 21542539.
- ↑ 3.0 3.1 3.2 3.3 Devouassoux-Shisheboran, M.; Silver, SA.; Tavassoli, FA. (Jul 1999). "Wolffian adnexal tumor, so-called female adnexal tumor of probable Wolffian origin (FATWO): immunohistochemical evidence in support of a Wolffian origin.". Hum Pathol 30 (7): 856-63. PMID 10414506.