Difference between revisions of "Female adnexal tumour of probable Wolffian origin"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Female adnexal tumour of probable Wolffian origin - very high mag.jpg
| Width      =
| Caption    = FATWO. [[H&E stain]].
| Micro      =
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        = vimentin +ve, AE1/AE3 +ve, CAM5.2 +ve, AR +ve (~80% of cases)
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = adnexa ([[ovary]])
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = very rare
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = usu. benign
| Other      =
| ClinDDx    =
}}
'''Female adnexal tumour of probable Wolffian origin''', abbreviated '''FATWO''', is a rare usually benign tumour.
'''Female adnexal tumour of probable Wolffian origin''', abbreviated '''FATWO''', is a rare usually benign tumour.


It is also known as '''Wolffian adnexal tumour'''.
It is also known as '''Wolffian adnexal tumour''', abbreviated '''WAT'''.


==General==
==General==

Latest revision as of 03:23, 23 April 2015

Female adnexal tumour of probable Wolffian origin
Diagnosis in short

FATWO. H&E stain.
IHC vimentin +ve, AE1/AE3 +ve, CAM5.2 +ve, AR +ve (~80% of cases)
Site adnexa (ovary)
Prevalence very rare
Prognosis usu. benign

Female adnexal tumour of probable Wolffian origin, abbreviated FATWO, is a rare usually benign tumour.

It is also known as Wolffian adnexal tumour, abbreviated WAT.

General

  • Super rare.[1]
  • Usually benign.
    • May be malignant.[2]

Gross

Adnexal location - as the name suggests:[3]

  • Broad ligament of ovary.
  • Mesosalpinx.
  • Ovarian hilus - less common.

Microscopic

Features:[3]

  • Variable architecture:
    • Tubular or glandular.
    • Solid - spindle cells.
    • Multicystic.

DDx:

Images

  • FATWO - intermed. mag.

  • FATWO - high mag.

  • FATWO - very high mag.

IHC

Features:[3]

  • Vimentin +ve.
  • AE1/AE3 +ve.
  • CAM5.2 +ve.
  • CK7 +ve -- focal, sometimes -ve.
  • AR +ve ~80% of cases.
  • Inhibin +ve ~70% of cases.

Others:[3]

  • CK20 -ve.
  • mCEA -ve.

See also

References

  1. ↑ Tianmin, X.; Weiqim, C.; Mianhua, C.; Xiaocui, L.; Hongwen, G.; Min, Y. (2012). "Tumor of the mesosalpinx: case report of a female adnexal tumor of probable Wolffian origin.". Eur J Gynaecol Oncol 33 (2): 233-5. PMID 22611973.
  2. ↑ Heller, DS.; Kadire, B.; Cracchiolo, B.. "Malignant female adnexal tumor of probable Wolffian origin: a case report.". J Reprod Med 56 (3-4): 175-7. PMID 21542539.
  3. ↑ 3.0 3.1 3.2 3.3 Devouassoux-Shisheboran, M.; Silver, SA.; Tavassoli, FA. (Jul 1999). "Wolffian adnexal tumor, so-called female adnexal tumor of probable Wolffian origin (FATWO): immunohistochemical evidence in support of a Wolffian origin.". Hum Pathol 30 (7): 856-63. PMID 10414506.
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