Difference between revisions of "Post-inflammatory pigment alteration"
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'''Post-inflammatory pigment alteration''', abbreviated '''PIPA''', is benign dermal pigmentation change. It may be either hyperpigmentation or hypopigmentation.<ref>{{Cite journal | last1 = Cardinali | first1 = G. | last2 = Kovacs | first2 = D. | last3 = Picardo | first3 = M. | title = Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo. | journal = Ann Dermatol Venereol | volume = 139 Suppl 4 | issue = | pages = S148-52 | month = Dec | year = 2012 | doi = 10.1016/S0151-9638(12)70127-8 | PMID = 23522630 }}</ref> | '''Post-inflammatory pigment alteration''', abbreviated '''PIPA''', is benign dermal pigmentation change. It may be either hyperpigmentation or hypopigmentation.<ref>{{Cite journal | last1 = Cardinali | first1 = G. | last2 = Kovacs | first2 = D. | last3 = Picardo | first3 = M. | title = Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo. | journal = Ann Dermatol Venereol | volume = 139 Suppl 4 | issue = | pages = S148-52 | month = Dec | year = 2012 | doi = 10.1016/S0151-9638(12)70127-8 | PMID = 23522630 }}</ref> | ||
'''Post-inflammatory hyperpigmentation''' and '''post-inflammatory hypopigmentation''' redirect here. | |||
==General== | ==General== | ||
Clinical DDx: | Clinical DDx: | ||
*[[Melanocytic lesions]] - esp. [[malignant melanoma]]. | *[[Melanocytic lesions]] - esp. [[malignant melanoma]]. | ||
==Gross== | |||
*Hyperpigmentation or hypopigmentation. | |||
Images: | |||
*[http://www.dermnetnz.org/colour/postinflammatory-pigmentation.html Post-inflammatory hyperpigmentation (dermnetnz.org)]. | |||
==Microscopic== | ==Microscopic== | ||
Latest revision as of 15:11, 15 January 2014
Post-inflammatory pigment alteration, abbreviated PIPA, is benign dermal pigmentation change. It may be either hyperpigmentation or hypopigmentation.[1]
Post-inflammatory hyperpigmentation and post-inflammatory hypopigmentation redirect here.
General
Clinical DDx:
Gross
- Hyperpigmentation or hypopigmentation.
Images:
Microscopic
Features:
- Perivascular pigment incontinence.
- No melanocytic nests.
- No increase of melanocytes.
DDx:
- Ephelis (freckle).
- Solar lentigo.
Stains
- Fontana-Masson stain +ve.
- Iron stain -ve.
See also
References
- ↑ Cardinali, G.; Kovacs, D.; Picardo, M. (Dec 2012). "Mechanisms underlying post-inflammatory hyperpigmentation: lessons from solar lentigo.". Ann Dermatol Venereol 139 Suppl 4: S148-52. doi:10.1016/S0151-9638(12)70127-8. PMID 23522630.