Difference between revisions of "Mesonephric remnant of the prostate gland"

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Line 28: Line 28:
*[[PAX8]] +ve.
*[[PAX8]] +ve.
*[[PSA]] -ve (all).
*[[PSA]] -ve (all).
*[[PSAP]] -ve.<ref name=pmid12861057>{{Cite journal  | last1 = Bostwick | first1 = DG. | last2 = Qian | first2 = J. | last3 = Ma | first3 = J. | last4 = Muir | first4 = TE. | title = Mesonephric remnants of the prostate: incidence and histologic spectrum. | journal = Mod Pathol | volume = 16 | issue = 7 | pages = 630-5 | month = Jul | year = 2003 | doi = 10.1097/01.MP.0000074733.10777.78 | PMID = 12861057 }</ref>
*[[PSAP]] -ve.<ref name=pmid12861057/>
*[[CK34betaE12]] +ve/-ve (diffuse +ve in 4/7 cases)
*[[CK34betaE12]] +ve/-ve (diffuse +ve in 4/7 cases)
*[[p63]] -ve.
*[[p63]] -ve.

Latest revision as of 14:52, 4 August 2022

Mesonephric remnant of the prostate gland, also mesonephric remnant, is rare benign finding in the prostate gland that can be confused with prostate carcinoma.

This article also deals with mesonephric remnant hyperplasia.

General

  • Very rare[1] ~ 0.6% incidence in a series of almost 700 TURP specimens.[2]
  • Can mimic prostate carcinoma.[3]

Microscopic

Features:[1]

  • Small glands in a lobular arrangement composed of cuboidal cells with:
    • Scant-to-moderate cytoplasm.[2]
    • Small/indistinct nucleoli.

Note:

  • May look like Gleason pattern 3 adenocarcinoma.

DDx:[1]

Images

www:

IHC

Features:[1]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Chen, YB.; Fine, SW.; Epstein, JI. (Jul 2011). "Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy.". Am J Surg Pathol 35 (7): 1054-61. doi:10.1097/PAS.0b013e318218df97. PMID 21606823.
  2. ↑ 2.0 2.1 2.2 2.3 Bostwick, DG.; Qian, J.; Ma, J.; Muir, TE. (Jul 2003). "Mesonephric remnants of the prostate: incidence and histologic spectrum.". Mod Pathol 16 (7): 630-5. doi:10.1097/01.MP.0000074733.10777.78. PMID 12861057.
  3. ↑ Yacoub, M.; Milin, S.; Irani, J.; Fromont, G. (Dec 2009). "Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer.". Ann Diagn Pathol 13 (6): 402-4. doi:10.1016/j.anndiagpath.2009.03.008. PMID 19917478.
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