Difference between revisions of "Compound nevus"
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'''Compound nevus''' (abbreviated '''CN'''), also '''compound melanocytic nevus''' (abbreviated '''CMN'''), is a common benign [[melanocytic lesion]]. | |||
The ''compound nevus'' is in the large group '''[[common nevus]]'''. In common language, ''nevus'' is known as a ''mole''. | |||
==General== | |||
*Benign. | |||
*Common. | |||
*Think ''[[melanoma]]''. | |||
Clinical: | |||
*''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large). | |||
==Microscopic== | |||
Features: | |||
*Symmetrical lesion. | |||
*"Matures" with depth | |||
**Less cellular with depth | |||
**Less nuclear atypia with depth. | |||
**Smaller cells with depth. | |||
**Smaller nests with depth. | |||
*Rare mitoses (superficial). | |||
**No deep mitoses. | |||
*No destruction of surrounding structures. | |||
*No nucleoli. | |||
*In the dermis '''and''' epidermis - '''key feature'''. | |||
*+/-Adipocytes - uncommon.<ref name=pmid9810886>{{Cite journal | last1 = Eng | first1 = W. | last2 = Cohen | first2 = PR. | title = Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells. | journal = J Am Acad Dermatol | volume = 39 | issue = 5 Pt 1 | pages = 704-11 | month = Nov | year = 1998 | doi = | PMID = 9810886 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image: Compound nevus -- low mag.jpg | CN - low mag. | |||
Image: Compound nevus -- intermed mag.jpg | CN - intermed. mag. | |||
Image: Compound nevus -- high mag.jpg | CN - high mag. | |||
Image: Compound nevus - alt -- high mag.jpg | CN - high mag. | |||
Image: Compound nevus -- very high mag.jpg | CN - very high mag. | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
SKIN LESION, RIGHT NECK, SHAVE BIOPSY: | |||
- BENIGN COMPOUND NEVUS. | |||
</pre> | |||
===Micro=== | |||
The sections show melanocytes in the dermis and epidermis. The lesion is symmetrical in its architecture and pigment distribution. There is no pagetoid spread of melanocytes in the epidermis. Superficially, melanocytes are in nests. Melanocytes show no apparent cytologic atypia and mature with depth. No mitotic activity is appreciated. | |||
The lesion is completely excised in the plane of section. | |||
====Barely compound==== | |||
The sections show melanocytes predominantly in the dermis. Rare melanocytic nests are seen at the dermal-epidermal junction. There is no pagetoid spread of melanocytes in the epidermis. The lesion is symmetrical in its architecture. Superficially, melanocytes are in nests and pigment is present. The melanocytes mature with depth. No mitotic activity is appreciated. | |||
The lesion is present at the margin. | |||
==See also== | |||
*[[Melanocytic lesions]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Melanocytic lesions]] | |||
[[Category:Diagnosis]] | |||
Revision as of 04:25, 25 January 2014
Compound nevus (abbreviated CN), also compound melanocytic nevus (abbreviated CMN), is a common benign melanocytic lesion.
The compound nevus is in the large group common nevus. In common language, nevus is known as a mole.
General
- Benign.
- Common.
- Think melanoma.
Clinical:
- ABCD = asymmetric, borders (irregular), colour (black), diameter (large).
Microscopic
Features:
- Symmetrical lesion.
- "Matures" with depth
- Less cellular with depth
- Less nuclear atypia with depth.
- Smaller cells with depth.
- Smaller nests with depth.
- Rare mitoses (superficial).
- No deep mitoses.
- No destruction of surrounding structures.
- No nucleoli.
- In the dermis and epidermis - key feature.
- +/-Adipocytes - uncommon.[1]
Images
CN - low mag.
CN - intermed. mag.
CN - high mag.
CN - high mag.
CN - very high mag.
Sign out
SKIN LESION, RIGHT NECK, SHAVE BIOPSY: - BENIGN COMPOUND NEVUS.
Micro
The sections show melanocytes in the dermis and epidermis. The lesion is symmetrical in its architecture and pigment distribution. There is no pagetoid spread of melanocytes in the epidermis. Superficially, melanocytes are in nests. Melanocytes show no apparent cytologic atypia and mature with depth. No mitotic activity is appreciated.
The lesion is completely excised in the plane of section.
Barely compound
The sections show melanocytes predominantly in the dermis. Rare melanocytic nests are seen at the dermal-epidermal junction. There is no pagetoid spread of melanocytes in the epidermis. The lesion is symmetrical in its architecture. Superficially, melanocytes are in nests and pigment is present. The melanocytes mature with depth. No mitotic activity is appreciated.
The lesion is present at the margin.