Difference between revisions of "Angiolymphoid hyperplasia with eosinophilia"

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(+DDx lymphoma)
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*Very rare.
*Very rare.
*Typical patient: Caucasian, woman.<ref name=pmid21382284/>
*Typical patient: Caucasian, woman.<ref name=pmid21382284/>
*Hypothesized to be a precursor to lymphoma.<ref name=pmid18510751>{{Cite journal  | last1 = Gonzalez-Cuyar | first1 = LF. | last2 = Tavora | first2 = F. | last3 = Zhao | first3 = XF. | last4 = Wang | first4 = G. | last5 = Auerbach | first5 = A. | last6 = Aguilera | first6 = N. | last7 = Burke | first7 = AP. | title = Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process. | journal = Diagn Pathol | volume = 3 | issue =  | pages = 22 | month =  | year = 2008 | doi = 10.1186/1746-1596-3-22 | PMID = 18510751 }}</ref>


Clinical:
Clinical:
*Skin papules ''or'' nodules.<ref name=pmid8733384>{{Cite journal  | last1 = Bartralot | first1 = R. | last2 = Garcia-Patos | first2 = V. | last3 = Hueto | first3 = J. | last4 = Huguet | first4 = P. | last5 = Raspall | first5 = G. | last6 = Castells | first6 = A. | title = Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature. | journal = Br J Dermatol | volume = 134 | issue = 4 | pages = 744-8 | month = Apr | year = 1996 | doi =  | PMID = 8733384 }}</ref>
*Skin papules ''or'' nodules.<ref name=pmid8733384>{{Cite journal  | last1 = Bartralot | first1 = R. | last2 = Garcia-Patos | first2 = V. | last3 = Hueto | first3 = J. | last4 = Huguet | first4 = P. | last5 = Raspall | first5 = G. | last6 = Castells | first6 = A. | title = Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature. | journal = Br J Dermatol | volume = 134 | issue = 4 | pages = 744-8 | month = Apr | year = 1996 | doi =  | PMID = 8733384 }}</ref>
*Location: usu. head and neck.
*Location: usually head and neck.<ref name=pmid18510751/>


==Microscopic==
==Microscopic==
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*[[Angiosarcoma]].
*[[Angiosarcoma]].
*[[Kaposi sarcoma]].
*[[Kaposi sarcoma]].
*[[Lymphoma]].


==See also==
==See also==

Revision as of 21:15, 15 April 2012

Angiolymphoid hyperplasia with eosinophilia, abbreviated ALHE, is a rare skin pathology.

General

  • Similar to Kimura disease.[1]
  • Very rare.
  • Typical patient: Caucasian, woman.[1]
  • Hypothesized to be a precursor to lymphoma.[2]

Clinical:

  • Skin papules or nodules.[3]
  • Location: usually head and neck.[2]

Microscopic

Features:[1]

  • Marked vascular proliferation.
  • Few lymphoid follicles.
  • Moderate eosinophils.

Negative:

  • No fibrosis.

DDx:

See also

References

  1. 1.0 1.1 1.2 Zaraa, I.; Mlika, M.; Chouk, S.; Chelly, I.; Mokni, M.; Zitouna, M.; Osman, AB. (2011). "Angiolymphoid hyperplasia with eosinophilia: a study of 7 cases.". Dermatol Online J 17 (2): 1. PMID 21382284.
  2. 2.0 2.1 Gonzalez-Cuyar, LF.; Tavora, F.; Zhao, XF.; Wang, G.; Auerbach, A.; Aguilera, N.; Burke, AP. (2008). "Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process.". Diagn Pathol 3: 22. doi:10.1186/1746-1596-3-22. PMID 18510751.
  3. Bartralot, R.; Garcia-Patos, V.; Hueto, J.; Huguet, P.; Raspall, G.; Castells, A. (Apr 1996). "Angiolymphoid hyperplasia with eosinophilia affecting the oral mucosa: report of a case and a review of the literature.". Br J Dermatol 134 (4): 744-8. PMID 8733384.