Difference between revisions of "Malakoplakia"
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==Microscopic== | ==Microscopic== | ||
Features:<ref>{{Ref PBoD|1027}}</ref> | Features:<ref>{{Ref PBoD|1027}}</ref> | ||
*Basophilic calcified lysosomes (Michaelis-Gutmann bodies) -- '''key feature'''. | |||
**May be inside or outside of macrophages - often size of [[RBC]] or larger. | |||
*Large foamy macrophages with granular cytoplasm. | *Large foamy macrophages with granular cytoplasm. | ||
*Occasional multinucleated giant cell. | *Occasional multinucleated giant cell. | ||
*Lymphocytes. | *Lymphocytes. | ||
Images: | Images: | ||
*[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675(06)70342-4&figureId=fig5&ecomponentId=mmc5 Malakoplakia (pathconsultddx.com)] | *[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675(06)70342-4&figureId=fig5&ecomponentId=mmc5 Malakoplakia (pathconsultddx.com)] | ||
*[http://granuloma.homestead.com/malakoplakia_bladder_s92-4486e.jpg Malakoplakia (granuloma.homstead.com)]. | *[http://granuloma.homestead.com/malakoplakia_bladder_s92-4486e.jpg Malakoplakia (granuloma.homstead.com)]. | ||
*[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=13&cat3=342&stype=d Michaelis-Gutmann bodies (gfmer.ch)]. | |||
==See also== | ==See also== | ||
Revision as of 05:22, 9 September 2010
Malakoplakia is a thingy that typically arises in the bladder.
Gross
- Yellow mass.[1]
- May mimic renal cell carcinoma.
Microscopic
Features:[2]
- Basophilic calcified lysosomes (Michaelis-Gutmann bodies) -- key feature.
- May be inside or outside of macrophages - often size of RBC or larger.
- Large foamy macrophages with granular cytoplasm.
- Occasional multinucleated giant cell.
- Lymphocytes.
Images:
- Malakoplakia (pathconsultddx.com)
- Malakoplakia (granuloma.homstead.com).
- Michaelis-Gutmann bodies (gfmer.ch).
See also
References
- ↑ URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70719-7. Accessed on: 9 September 2010.
- ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 1027. ISBN 0-7216-0187-1.