Difference between revisions of "Peritoneum"
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*Serum CA-125 usually low. | *Serum CA-125 usually low. | ||
*May occur in men.<ref name=pmid12239771>{{Cite journal | last1 = Cavallaro | first1 = A. | last2 = Murazio | first2 = M. | last3 = Modugno | first3 = P. | last4 = Vona | first4 = A. | last5 = Revelli | first5 = L. | last6 = Potenza | first6 = AE. | last7 = Colli | first7 = R. | title = Benign multicystic mesothelioma of the peritoneum: a case report. | journal = Chir Ital | volume = 54 | issue = 4 | pages = 569-72 | month = | year = | doi = | PMID = 12239771 }}</ref> | *May occur in men.<ref name=pmid12239771>{{Cite journal | last1 = Cavallaro | first1 = A. | last2 = Murazio | first2 = M. | last3 = Modugno | first3 = P. | last4 = Vona | first4 = A. | last5 = Revelli | first5 = L. | last6 = Potenza | first6 = AE. | last7 = Colli | first7 = R. | title = Benign multicystic mesothelioma of the peritoneum: a case report. | journal = Chir Ital | volume = 54 | issue = 4 | pages = 569-72 | month = | year = | doi = | PMID = 12239771 }}</ref> | ||
===Gross=== | |||
Features:<ref name=pmid3789251>{{Cite journal | last1 = McFadden | first1 = DE. | last2 = Clement | first2 = PB. | title = Peritoneal inclusion cysts with mural mesothelial proliferation. A clinicopathological analysis of six cases. | journal = Am J Surg Pathol | volume = 10 | issue = 12 | pages = 844-54 | month = Dec | year = 1986 | doi = | PMID = 3789251 }}</ref> | |||
*Multilocular thin-walled cysts containing serous fluid +/- blood. | |||
**Occasionally unilocular. | |||
*May be up to 15 cm. | |||
*Can be adherent to the [[ovary]]. | |||
===Microscopic=== | ===Microscopic=== | ||
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**Mesothelial lining. | **Mesothelial lining. | ||
**Eosinophilic fluid. | **Eosinophilic fluid. | ||
DDx: | |||
*[[Ovarian serous borderline tumour]]. | |||
Images: | Images: | ||
Revision as of 19:51, 18 October 2012
The peritoneum is a much neglected area, with relatively little pathology. It includes the omentum which is dealt with in the omentum article.
Benign
Peritoneal implants
Main article: Peritoneal implants
- These are dealt with in the ovarian tumours article. Broadly speaking they may be: (1) desmoplastic non-invasive, (2) epithelial non-invasive, and (3) invasive.
Well-differentiated papillary mesothelioma
- Should not be confused with malignant mesothelioma or benign multicystic mesothelioma.
- AKA benign papillary mesothelioma.
General
Gross
Features - typical:
- Multiple peritoneal nodules.
- Ascites.
DDx:[1]
- Tuberculosis.
- Carcinomatosis.
- Primary peritoneal serous carcinoma.
Microscopic
Features:
- Papillary structures with:
- Thick fibrous cores.
- Simple cuboidal epithelium.
- Small nucleoli.
Note:
- Lack cytologic atypia.
Image:
Benign multicystic mesothelioma
- Should not be confused with malignant mesothelioma and benign papillary mesothelioma.
- AKA peritoneal inclusion cyst.[3]
- AKA inflammatory cyst of the peritoneum.
- AKA mesothelial inclusion cyst. (???)
General
- Usually conservative management.
- Serum CA-125 usually low.
- May occur in men.[4]
Gross
Features:[5]
- Multilocular thin-walled cysts containing serous fluid +/- blood.
- Occasionally unilocular.
- May be up to 15 cm.
- Can be adherent to the ovary.
Microscopic
- Thin-walled, irregular-shaped, cysts - unicystic or multicystic.
- Mesothelial lining.
- Eosinophilic fluid.
DDx:
Images:
IHC
Features:[7]
- Calretinin +ve.
- WT-1 +ve.
- D2-40 -ve. (???)
Malignant
Primary peritoneal serous carcinoma
General
- Very rare.
- Reported in men.[8]
Microscopic
Features:
- Like serous carcinoma elsewhere - see ovarian serous carcinoma.
- To exclude ovarian serous carcinoma all of the following criteria must be met:[9]
- Histology of the tumour = serous carcinoma.
- Bulk of the tumour involves the peritoneum.
- Ovarian substance tumour extent less than 5 x 5 mm in plane of section.
- Previous ovarian serous carcinoma is excluded.
- Old oopherectomies reviewed if possible.
DDx:
- Ovarian serous carcinoma.
- Other serous carcinomas - see serous carcinoma.
- Malignant mesothelioma.
IHC
- Like serous carcinoma elsewhere - see ovarian serous carcinoma.
Malignant mesothelioma
Main article: Malignant mesothelioma
This is like the tumour found in the pleural cavity.
See also
References
- ↑ 1.0 1.1 Park, JY.; Kim, KW.; Kwon, HJ.; Park, MS.; Kwon, GY.; Jun, SY.; Yu, ES. (Sep 2008). "Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis.". AJR Am J Roentgenol 191 (3): 814-25. doi:10.2214/AJR.07.3628. PMID 18716115.
- ↑ Chetty, R. (Nov 1992). "Well differentiated (benign) papillary mesothelioma of the tunica vaginalis.". J Clin Pathol 45 (11): 1029-30. PMID 1452778.
- ↑ 3.0 3.1 Vallerie, AM.; Lerner, JP.; Wright, JD.; Baxi, LV. (May 2009). "Peritoneal inclusion cysts: a review.". Obstet Gynecol Surv 64 (5): 321-34. doi:10.1097/OGX.0b013e31819f93d4. PMID 19386139.
- ↑ Cavallaro, A.; Murazio, M.; Modugno, P.; Vona, A.; Revelli, L.; Potenza, AE.; Colli, R.. "Benign multicystic mesothelioma of the peritoneum: a case report.". Chir Ital 54 (4): 569-72. PMID 12239771.
- ↑ McFadden, DE.; Clement, PB. (Dec 1986). "Peritoneal inclusion cysts with mural mesothelial proliferation. A clinicopathological analysis of six cases.". Am J Surg Pathol 10 (12): 844-54. PMID 3789251.
- ↑ Levy, AD.; Arnáiz, J.; Shaw, JC.; Sobin, LH.. "From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation.". Radiographics 28 (2): 583-607; quiz 621-2. doi:10.1148/rg.282075175. PMID 18349460.
- ↑ 7.0 7.1 Takemoto, S.; Kawano, R.; Honda, K.; Nakazono, A.; Shimamatsu, K. (2012). "Benign multicystic peritoneal mesothelioma mimicking recurrence of an ovarian borderline tumor: a case report.". J Med Case Rep 6 (1): 126. doi:10.1186/1752-1947-6-126. PMID 22583977.
- ↑ Shmueli, E.; Leider-Trejo, L.; Schwartz, I.; Aderka, D.; Inbar, M. (Apr 2001). "Primary papillary serous carcinoma of the peritoneum in a man.". Ann Oncol 12 (4): 563-7. PMID 11398893.
- ↑ Roh, SY.; Hong, SH.; Ko, YH.; Kim, TH.; Lee, MA.; Shim, BY.; Byun, JH.; Woo, IS. et al. (Jun 2007). "Clinical characteristics of primary peritoneal carcinoma.". Cancer Res Treat 39 (2): 65-8. doi:10.4143/crt.2007.39.2.65. PMC 273931. PMID 19746214. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC273931/.