Difference between revisions of "Female adnexal tumour of probable Wolffian origin"

From Libre Pathology
Jump to navigation Jump to search
Line 5: Line 5:
==General==
==General==
*Super rare.<ref name=pmid22611973>{{Cite journal  | last1 = Tianmin | first1 = X. | last2 = Weiqim | first2 = C. | last3 = Mianhua | first3 = C. | last4 = Xiaocui | first4 = L. | last5 = Hongwen | first5 = G. | last6 = Min | first6 = Y. | title = Tumor of the mesosalpinx: case report of a female adnexal tumor of probable Wolffian origin. | journal = Eur J Gynaecol Oncol | volume = 33 | issue = 2 | pages = 233-5 | month =  | year = 2012 | doi =  | PMID = 22611973 }}</ref>
*Super rare.<ref name=pmid22611973>{{Cite journal  | last1 = Tianmin | first1 = X. | last2 = Weiqim | first2 = C. | last3 = Mianhua | first3 = C. | last4 = Xiaocui | first4 = L. | last5 = Hongwen | first5 = G. | last6 = Min | first6 = Y. | title = Tumor of the mesosalpinx: case report of a female adnexal tumor of probable Wolffian origin. | journal = Eur J Gynaecol Oncol | volume = 33 | issue = 2 | pages = 233-5 | month =  | year = 2012 | doi =  | PMID = 22611973 }}</ref>
*Adnexal - as the name suggests.
*Usually benign.
*Usually benign.
**May be malignant.<ref name=pmid21542539>{{Cite journal  | last1 = Heller | first1 = DS. | last2 = Kadire | first2 = B. | last3 = Cracchiolo | first3 = B. | title = Malignant female adnexal tumor of probable Wolffian origin: a case report. | journal = J Reprod Med | volume = 56 | issue = 3-4 | pages = 175-7 | month =  | year =  | doi =  | PMID = 21542539 }}</ref>
**May be malignant.<ref name=pmid21542539>{{Cite journal  | last1 = Heller | first1 = DS. | last2 = Kadire | first2 = B. | last3 = Cracchiolo | first3 = B. | title = Malignant female adnexal tumor of probable Wolffian origin: a case report. | journal = J Reprod Med | volume = 56 | issue = 3-4 | pages = 175-7 | month =  | year =  | doi =  | PMID = 21542539 }}</ref>
==Gross=
Adnexal location - as the name suggests:<ref name=pmid10414506/>
*Broad ligament of ovary.
*Mesosalpinx.
*Ovarian hilus - less common.


==Microscopic==
==Microscopic==

Revision as of 22:59, 27 November 2013

Female adnexal tumour of probable Wolffian origin, abbreviated FATWO, is a rare usually benign tumour.

It is also known as Wolffian adnexal tumour.

General

  • Super rare.[1]
  • Usually benign.
    • May be malignant.[2]

=Gross

Adnexal location - as the name suggests:[3]

  • Broad ligament of ovary.
  • Mesosalpinx.
  • Ovarian hilus - less common.

Microscopic

Features:[3]

  • Variable architecture:
    • Tubular or glandular.
    • Solid - spindle cells.
    • Multicystic.

DDx:

Images

IHC

Features:[3]

  • Vimentin +ve.
  • AE1/AE3 +ve.
  • CAM5.2 +ve.
  • CK7 +ve -- focal, sometimes -ve.
  • AR +ve ~80% of cases.
  • Inhibin +ve ~70% of cases.

Others:[3]

  • CK20 -ve.
  • mCEA -ve.

See also

References

  1. Tianmin, X.; Weiqim, C.; Mianhua, C.; Xiaocui, L.; Hongwen, G.; Min, Y. (2012). "Tumor of the mesosalpinx: case report of a female adnexal tumor of probable Wolffian origin.". Eur J Gynaecol Oncol 33 (2): 233-5. PMID 22611973.
  2. Heller, DS.; Kadire, B.; Cracchiolo, B.. "Malignant female adnexal tumor of probable Wolffian origin: a case report.". J Reprod Med 56 (3-4): 175-7. PMID 21542539.
  3. 3.0 3.1 3.2 3.3 Devouassoux-Shisheboran, M.; Silver, SA.; Tavassoli, FA. (Jul 1999). "Wolffian adnexal tumor, so-called female adnexal tumor of probable Wolffian origin (FATWO): immunohistochemical evidence in support of a Wolffian origin.". Hum Pathol 30 (7): 856-63. PMID 10414506.