Difference between revisions of "Mesonephric remnant of the prostate gland"

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==Microscopic==
==Microscopic==
Features:<ref name=pmid21606823/>
Features:<ref name=pmid21606823/>
*Small glands with small bland appearing cuboidal cells in a lobular arrangement.
*Small glands in a lobular arrangement composed of cuboidal cells with:
**Scant-to-moderate cytoplasm.<ref name=pmid12861057/>
**Small/indistinct nucleoli.


DDx:<ref name=pmid21606823/>
DDx:<ref name=pmid21606823/>

Revision as of 14:43, 9 April 2014

Mesonephric remnant hyperplasia of the prostate gland, also mesonephric remnant, is rare benign finding in the prostate gland that can be confused with malignancy.

General

  • Very rare.[1] ~ 0.6% incidence in a series of almost 700 TURP specimens.[2]
  • Can mimic prostate carcinoma.[3]

Microscopic

Features:[1]

  • Small glands in a lobular arrangement composed of cuboidal cells with:
    • Scant-to-moderate cytoplasm.[2]
    • Small/indistinct nucleoli.

DDx:[1]

Images

www:

IHC

Features:[1]

  • PAX8 +ve.
  • PSA -ve (all).
  • PSAP -ve.[2]
  • CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
  • p63 -ve.
  • AMACR +ve (focal).

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Chen, YB.; Fine, SW.; Epstein, JI. (Jul 2011). "Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy.". Am J Surg Pathol 35 (7): 1054-61. doi:10.1097/PAS.0b013e318218df97. PMID 21606823.
  2. ↑ 2.0 2.1 2.2 2.3 Bostwick, DG.; Qian, J.; Ma, J.; Muir, TE. (Jul 2003). "Mesonephric remnants of the prostate: incidence and histologic spectrum.". Mod Pathol 16 (7): 630-5. doi:10.1097/01.MP.0000074733.10777.78. PMID 12861057. Cite error: Invalid <ref> tag; name "pmid12861057" defined multiple times with different content
  3. ↑ Yacoub, M.; Milin, S.; Irani, J.; Fromont, G. (Dec 2009). "Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer.". Ann Diagn Pathol 13 (6): 402-4. doi:10.1016/j.anndiagpath.2009.03.008. PMID 19917478.
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