Difference between revisions of "Mesonephric remnant of the prostate gland"
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Revision as of 14:43, 9 April 2014
Mesonephric remnant hyperplasia of the prostate gland, also mesonephric remnant, is rare benign finding in the prostate gland that can be confused with malignancy.
General
- Very rare.[1] ~ 0.6% incidence in a series of almost 700 TURP specimens.[2]
- Can mimic prostate carcinoma.[3]
Microscopic
Features:[1]
- Small glands in a lobular arrangement composed of cuboidal cells with:
- Scant-to-moderate cytoplasm.[2]
- Small/indistinct nucleoli.
DDx:[1]
- Sclerosing adenosis of the prostate gland.
- Prostate carcinoma - esp. Gleason pattern 5.
Images
www:
IHC
Features:[1]
- PAX8 +ve.
- PSA -ve (all).
- PSAP -ve.[2]
- CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
- p63 -ve.
- AMACR +ve (focal).
See also
References
- ↑ 1.0 1.1 1.2 1.3 Chen, YB.; Fine, SW.; Epstein, JI. (Jul 2011). "Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy.". Am J Surg Pathol 35 (7): 1054-61. doi:10.1097/PAS.0b013e318218df97. PMID 21606823.
- ↑ 2.0 2.1 2.2 2.3 Bostwick, DG.; Qian, J.; Ma, J.; Muir, TE. (Jul 2003). "Mesonephric remnants of the prostate: incidence and histologic spectrum.". Mod Pathol 16 (7): 630-5. doi:10.1097/01.MP.0000074733.10777.78. PMID 12861057. Cite error: Invalid
<ref>tag; name "pmid12861057" defined multiple times with different content - ↑ Yacoub, M.; Milin, S.; Irani, J.; Fromont, G. (Dec 2009). "Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer.". Ann Diagn Pathol 13 (6): 402-4. doi:10.1016/j.anndiagpath.2009.03.008. PMID 19917478.