Difference between revisions of "Exaggerated placental site"

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DDx:
DDx:
*[[PSTT]].
*[[PSTT]].
===Image===
*[http://www.webpathology.com/image.asp?case=565&n=7 EPS (webpathology.com)].


==IHC==
==IHC==

Revision as of 15:46, 22 May 2014

Exaggerated placental site, abbreviated EPS, is an uncommon benign pathology that is a gestational trophoblastic disease.

It was previously known as syncytial endometritis.[1]

General

  • Benign.

Definition:

Note:

  • Used to go by a terrible old term: syncytial endometritis:[2]
    • Not syncytial -- mostly.
    • Not inflammatory.

Microscopic

Features:[2]

  • Intermediate trophoblast:
    • Abundant (eosinophilic) cytoplasm.
  • Usu. adjacent to:
    • Chorionic villi.
    • Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders.
  • No mitotic activity.
  • Ectatic blood vessels.

DDx:

Image

IHC

  • MIB1 ~0%.
    • Used to differentiate from PSTT.

See also

References