Difference between revisions of "Urothelial papilloma"

From Libre Pathology
Jump to navigation Jump to search
(more)
Line 1: Line 1:
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Urothelial papilloma - alt -- intermed mag.jpg
| Width      =
| Caption    = Urothelial papilloma. [[H&E stain]].
| Synonyms  =
| Micro      = papillary fronds with minimal branching or fusion, cytological and thickness of normal urothelium, no mitoses
| Subtypes  =
| LMDDx      = [[low grade papillary urothelial carcinoma]], [[PUNLMP]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[urothelium]] - typically [[urinary bladder]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = other papillary lesions
| Tx        =
}}
'''Urothelial papilloma''' is a rare benign lesion of the [[urothelium]].
'''Urothelial papilloma''' is a rare benign lesion of the [[urothelium]].



Revision as of 03:54, 13 June 2015

Urothelial papilloma
Diagnosis in short

Urothelial papilloma. H&E stain.

LM papillary fronds with minimal branching or fusion, cytological and thickness of normal urothelium, no mitoses
LM DDx low grade papillary urothelial carcinoma, PUNLMP
Site urothelium - typically urinary bladder

Prevalence uncommon
Prognosis benign
Clin. DDx other papillary lesions

Urothelial papilloma is a rare benign lesion of the urothelium.

General

  • Rare.[1]
  • Males > females (1.9:1).[1]

Notes:

  • If the person has a history of a low grade papillary urothelial carcinoma... it is likely a low grade papillary urothelial carcinoma.
  • These cases are a consensus diagnosis, i.e. you show it to a colleague... if they agree you can call it.

Gross

  • Exophytic lesion.

Microscopic

Features:[2]

  • Papillary fronds.
  • Minimal branching or fusion.
  • Cytological features of normal urothelium.
    • Normal urothelium approx. 2x the size of stromal lymphocytes.[3]
  • No mitoses.
  • Thickness < 7 cells.[citation needed]

DDx:

See also

References

  1. 1.0 1.1 Al Bashir, S.; Yilmaz, A.; Gotto, G.; Trpkov, K. (Jan 2014). "Long term outcome of primary urothelial papilloma: a single institution cohort.". Pathology 46 (1): 37-40. doi:10.1097/PAT.0000000000000029. PMID 24300727.
  2. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 310. ISBN 978-0781765275.
  3. Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 161. ISBN 978-0443066771.