Difference between revisions of "Cytokeratin 20"
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===Partially CK20 positive=== | ===Partially CK20 positive=== | ||
*Corticotroph [[pituitary | *Corticotroph [[pituitary adenoma]]s and [[Crooke-hyaline change]]s. <ref>{{Cite journal | last1 = Eschbacher | first1 = JM. | last2 = Coons | first2 = SW. | title = Cytokeratin CK20 is a sensitive marker for Crooke's cells and the early cytoskeletal changes associated with hypercortisolism within pituitary corticotrophs. | journal = Endocr Pathol | volume = 17 | issue = 4 | pages = 365-76 | month = | year = 2006 | doi = | PMID = 17525485 }}</ref> | ||
==See also== | ==See also== | ||
Revision as of 15:55, 16 June 2015
CK20 staining in small intestine.
Cytokeratin 20, abbreviated CK20, is a commonly used immunostain. It is also known as keratin 20.
Positive
CK20 positive and CK7 negative
- Virtually all colorectal carcinomas.[1]
- Merkel cell carcinoma - perinuclear dot-like pattern.
Partially CK20 positive
- Corticotroph pituitary adenomas and Crooke-hyaline changes. [2]
See also
References
- ↑ Chu, P.; Wu, E.; Weiss, LM. (Sep 2000). "Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases.". Mod Pathol 13 (9): 962-72. doi:10.1038/modpathol.3880175. PMID 11007036.
- ↑ Eschbacher, JM.; Coons, SW. (2006). "Cytokeratin CK20 is a sensitive marker for Crooke's cells and the early cytoskeletal changes associated with hypercortisolism within pituitary corticotrophs.". Endocr Pathol 17 (4): 365-76. PMID 17525485.