Difference between revisions of "Histiocytoses"
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| [http://commons.wikimedia.org/w/index.php?title=File:Emperipolesis_-_very_high_mag.jpg RDD (WC)] | | [http://commons.wikimedia.org/w/index.php?title=File:Emperipolesis_-_very_high_mag.jpg RDD (WC)] | ||
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| Langerhans cell histiocytosis | | [[Langerhans cell histiocytosis]] (LCH) | ||
| Reniform nuclei,<br>eosinophilic cytoplasm | | Reniform nuclei,<br>eosinophilic cytoplasm | ||
| Birbeck granules | | Birbeck granules | ||
Revision as of 03:49, 16 March 2011
Histiocytoses, singular histiocytosis, are a rare set of conditions affecting tissue macrophages.
Histiocytoses in a table
Features of histiocytoses:[1]
| Histologic features | EM features | CD68 | S-100 | CD1a | Image | |
|---|---|---|---|---|---|---|
| Macrophage | epithelioid cells, giant cells | - | + | - | - | Macrophages - CD68 (WC) |
| Erdheim-Chester disease | Touton giant cells | - | + | +/- | - | |
| Rosai-Dorfman | Emperipolesis | - | + | + | - | RDD (WC) |
| Langerhans cell histiocytosis (LCH) | Reniform nuclei, eosinophilic cytoplasm |
Birbeck granules | + | + | + | LCH (WC) |
Notes:
- EM = electron microscopy.
Langerhans cell histiocytosis
IHC
Langerin (CD207).[2]
See also
References
- ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 479. ISBN 978-0781740517.
- ↑ URL: http://www.ncbi.nlm.nih.gov/omim/604862. Accessed on: 2 February 2011.