Difference between revisions of "Keloid"
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==General== | ==General== | ||
*Sites of previous trauma/surgery, esp. in dark skinned individuals.<ref name=Ref_WMSP492>{{Ref WMSP|492}}</ref> | *Sites of previous trauma/surgery, esp. in dark skinned individuals.<ref name=Ref_WMSP492>{{Ref WMSP|492}}</ref> | ||
*Various treatments. | *Various treatments: | ||
**Injections: corticosteroid such as triamcinolone acetonide (''Kenalog'').<ref name=pmid25396172>{{Cite journal | last1 = Trisliana Perdanasari | first1 = A. | last2 = Lazzeri | first2 = D. | last3 = Su | first3 = W. | last4 = Xi | first4 = W. | last5 = Zheng | first5 = Z. | last6 = Ke | first6 = L. | last7 = Min | first7 = P. | last8 = Feng | first8 = S. | last9 = Zhang | first9 = YX. | title = Recent developments in the use of intralesional injections keloid treatment. | journal = Arch Plast Surg | volume = 41 | issue = 6 | pages = 620-9 | month = Nov | year = 2014 | doi = 10.5999/aps.2014.41.6.620 | PMID = 25396172 }}</ref> | **Surgery. | ||
**Radiotherapy. | |||
**Injections: corticosteroid such as triamcinolone acetonide (''Kenalog'').<ref name=pmid26758090>{{Cite journal | last1 = Acosta | first1 = S. | last2 = Ureta | first2 = E. | last3 = Yañez | first3 = R. | last4 = Oliva | first4 = N. | last5 = Searle | first5 = S. | last6 = Guerra | first6 = C. | title = Effectiveness of Intralesional Triamcinolone in the Treatment of Keloids in Children. | journal = Pediatr Dermatol | volume = 33 | issue = 1 | pages = 75-9 | month = Jan | year = 2016 | doi = 10.1111/pde.12746 | PMID = 26758090 }}</ref><ref name=pmid25396172>{{Cite journal | last1 = Trisliana Perdanasari | first1 = A. | last2 = Lazzeri | first2 = D. | last3 = Su | first3 = W. | last4 = Xi | first4 = W. | last5 = Zheng | first5 = Z. | last6 = Ke | first6 = L. | last7 = Min | first7 = P. | last8 = Feng | first8 = S. | last9 = Zhang | first9 = YX. | title = Recent developments in the use of intralesional injections keloid treatment. | journal = Arch Plast Surg | volume = 41 | issue = 6 | pages = 620-9 | month = Nov | year = 2014 | doi = 10.5999/aps.2014.41.6.620 | PMID = 25396172 }}</ref> | |||
Note: | Note: | ||
*Reported as "keloidal-type collagen"; the clinician decides between ''hypertrophic scar'' and ''keloid''. | *Reported as "keloidal-type collagen"; the clinician decides between ''hypertrophic scar'' and ''keloid''. | ||
Revision as of 18:11, 4 March 2016
| Keloid | |
|---|---|
| Diagnosis in short | |
 Keloid. H&E stain. | |
|
| |
| LM | thick collagen bundles - surrounded by paler staining fibroblasts, loss of adnexal structures |
| LM DDx | hypertrophic scar |
| Site | skin |
|
| |
| Clinical history | typically dark skinned individuals |
| Prognosis | benign |
| Keloid | |
|---|---|
| External resources | |
| Wikipedia | keloid |
- Hypertrophic scar redirects here.
Keloid is an uncommon abnormal scarring.
General
- Sites of previous trauma/surgery, esp. in dark skinned individuals.[1]
- Various treatments:
Note:
- Reported as "keloidal-type collagen"; the clinician decides between hypertrophic scar and keloid.
Gross
- Scar formation beyond the initial injury site.
Image
Keloid. (WC)
Microscopic
Features:[1]
- Thick collagen bundles - surrounded by paler staining fibroblasts - key feature.
- Lesion replaces adnexal structures, e.g. hair, sweat glands.
DDx:
- Hypertrophic scar.[4]
Images
Keloid - low mag. (WC/Nephron)
Keloid - intermed. mag. (WC/Nephron)
Keloid - high mag. (WC/Nephron)
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SKIN LESION, LEFT SCAPULA, EXCISION: - DERMAL SCAR WITH KELOIDAL-TYPE COLLAGEN, SEE COMMENT. COMMENT: The findings are consistent with a hypertrophic scar or keloid; clinical correlation is required.
Clinical provided
SKIN LESION, LEFT NIPPLE AREOLA, EXCISION: - DERMAL SCAR WITH KELOIDAL-TYPE COLLAGEN, CONSISTENT WITH HYPERTROPHIC SCAR.
See also
References
- ↑ 1.0 1.1 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 492. ISBN 978-0781765275.
- ↑ Acosta, S.; Ureta, E.; Yañez, R.; Oliva, N.; Searle, S.; Guerra, C. (Jan 2016). "Effectiveness of Intralesional Triamcinolone in the Treatment of Keloids in Children.". Pediatr Dermatol 33 (1): 75-9. doi:10.1111/pde.12746. PMID 26758090.
- ↑ Trisliana Perdanasari, A.; Lazzeri, D.; Su, W.; Xi, W.; Zheng, Z.; Ke, L.; Min, P.; Feng, S. et al. (Nov 2014). "Recent developments in the use of intralesional injections keloid treatment.". Arch Plast Surg 41 (6): 620-9. doi:10.5999/aps.2014.41.6.620. PMID 25396172.
- ↑ Gauglitz, GG.; Korting, HC.; Pavicic, T.; Ruzicka, T.; Jeschke, MG.. "Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.". Mol Med 17 (1-2): 113-25. doi:10.2119/molmed.2009.00153. PMC 3022978. PMID 20927486. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022978/.